2. Gene
  3. DDX24 - DEAD-box helicase 24 Gene

DDX24 - DEAD-box helicase 24 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 57062 | Gene type: protein coding

About DDX24

Cytogenetic location: 14q32.12 Genomic coordinates (GRCh38): 14:94,048,287-94,081,202 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 209 orthologues and 38 paralogues. Ubiquitous expression in testis (RPKM 90.5), adrenal (RPKM 75.8) and 25 other tissues.

Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the Other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. [provided by RefSeq, Jul 2008]

DDX24 Products(1)

mRNA Protein Name
NM_020414.4 NP_065147.1 ATP-dependent RNA helicase DDX24
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22113938 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DDX24 Protein Structure

DEAD

DEAD: DEAD/DEAH box helicase (216 - 511)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (608 - 681)

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  • 859 a.a.
Protein Preferred Names Protein Names

ATP-dependent RNA helicase DDX24

DEAD (Asp-Glu-Ala-Asp) box helicase 24

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03639 DDX24 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris DDX24 VGNC VGNC:39851
Felis catus DDX24 VGNC VGNC:61402
Macaca mulatta DDX24 VGNC VGNC:71618
Mus musculus DDX24 MGD MGI:1351337
Bos taurus DDX24 VGNC VGNC:27960
Rattus norvegicus DDX24 RGD RGD:727929