IGSF9 - immunoglobulin superfamily member 9 Gene

Homo sapiens

Also known as Nrt1; IGSF9A; FP18798

Gene ID: 57549 | Gene type: protein coding

About IGSF9

Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:159,927,041-159,945,613 (from NCBI)

This gene has 5 transcripts (splice variants), 121 orthologues and 36 paralogues. Biased expression in skin (RPKM 12.2), stomach (RPKM 7.5) and 8 other tissues.

Summary

Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to act upstream of or within dendrite development and regulation of synapse organization. Predicted to be located in dendrite and inhibitory synapse. Predicted to be integral component of membrane. Predicted to be active in axon and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

IGSF9 Products(2)

mRNA	Protein	Name
NM_001135050.2	NP_001128522.1	protein turtle homolog A isoform a precursor
NM_020789.4	NP_065840.2	protein turtle homolog A isoform b precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IGSF9 Protein Structure

I-set

Ig_2

I-set

fn3

0
200
400
600
800
1000
1179 a.a.

Protein Preferred Names

Protein Names

protein turtle homolog A

immunoglobulin superfamily member 9A

Related Diseases

Diseases

Alias

Ovarian Endometrioid Stromal Sarcoma

Ovary Sarcoma

Sarcoma Of Ovary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06652	IGSF9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS06653	IGSF9B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	IGSF9	VGNC	VGNC:41919
Rattus norvegicus	IGSF9	RGD	RGD:1304566
Bos taurus	IGSF9	VGNC	VGNC:30097
Mus musculus	IGSF9	MGD	MGI:2135283
Macaca mulatta	IGSF9	VGNC	VGNC:73620
Felis catus	IGSF9	VGNC	VGNC:97462

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