2. Gene
  3. SYT13 - synaptotagmin 13 Gene

SYT13 - synaptotagmin 13 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 57586 | Gene type: protein coding

About SYT13

Cytogenetic location: 11p11.2 Genomic coordinates (GRCh38): 11:45,240,302-45,286,341 (from NCBI)

This gene has 3 transcripts (splice variants), 163 orthologues and 31 paralogues. Biased expression in brain (RPKM 27.1), gall bladder (RPKM 14.8) and 7 other tissues.

Summary

This gene encodes a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family members can form homo- and heteromeric complexes with each Other. They also have different biochemical properties and developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

SYT13 Products(2)

mRNA Protein Name
NM_001247987.2 NP_001234916.1 synaptotagmin-13 isoform 2
NM_020826.3 NP_065877.1 synaptotagmin-13 isoform 1

SYT13 Protein Structure

C2

C2: C2 domain (187 - 258)

C2

C2: C2 domain (305 - 393)

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  • 426 a.a.
Protein Preferred Names Protein Names

synaptotagmin-13

synaptotagmin XIII

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14110 SYT13 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SYT13 VGNC VGNC:65895
Mus musculus SYT13 MGD MGI:1933945
Rattus norvegicus SYT13 RGD RGD:621877
Canis familiaris SYT13 VGNC VGNC:47044
Bos taurus SYT13 VGNC VGNC:35539
Macaca mulatta SYT13 VGNC VGNC:78121