2. Gene
  3. HOMEZ - homeobox and leucine zipper encoding Gene

HOMEZ - homeobox and leucine zipper encoding Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as KIAA1443

Gene ID: 57594 | Gene type: protein coding

About HOMEZ

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:23,272,422-23,286,132 (from NCBI)

This gene has 5 transcripts (splice variants), 198 orthologues and 3 paralogues. Broad expression in testis (RPKM 9.5), urinary bladder (RPKM 4.3) and 24 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

HOMEZ Products(1)

mRNA Protein Name
NM_020834.3 NP_065885.2 homeobox and leucine zipper protein Homez
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HOMEZ Protein Structure

Homeobox_KN

Homeobox_KN: Homeobox KN domain (69 - 109)

Homez

Homez: Homeodomain leucine-zipper encoding, Homez (457 - 509)

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  • 550 a.a.
Protein Preferred Names Protein Names

homeobox and leucine zipper protein Homez

homeodomain leucine zipper-containing factor

Related Diseases

Diseases Alias
Joubert Syndrome 18

JBTS18

Joubert Syndrome, Type 18
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06286 HOMEZ Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris HOMEZ VGNC VGNC:41739
Mus musculus HOMEZ MGD MGI:2678023
Rattus norvegicus HOMEZ RGD RGD:628904
Bos taurus HOMEZ VGNC VGNC:29904
Felis catus HOMEZ VGNC VGNC:80955
Macaca mulatta HOMEZ VGNC VGNC:73426