ZDBF2 - zinc finger DBF-type containing 2 Gene

Homo sapiens

Also known as Slx9

Gene ID: 57683 | Gene type: protein coding

About ZDBF2

Cytogenetic location: 2q33.3 Genomic coordinates (GRCh38): 2:206,274,663-206,314,427 (from NCBI)

This gene has 10 transcripts (splice variants), 1 gene allele and 93 orthologues. Ubiquitous expression in adrenal (RPKM 4.6), brain (RPKM 4.3) and 25 other tissues.

Summary

This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

ZDBF2 Products(3)

mRNA	Protein	Name
NM_001285549.2	NP_001272478.1	DBF4-type zinc finger-containing protein 2 isoform 2
NM_001369654.1	NP_001356583.1	DBF4-type zinc finger-containing protein 2 isoform 1
NM_020923.3	NP_065974.1	DBF4-type zinc finger-containing protein 2 isoform 1

ZDBF2 Protein Structure

zf-DBF

0
400
800
1200
1600
2000
2354 a.a.

Protein Preferred Names

Protein Names

DBF4-type zinc finger-containing protein 2

Related Diseases

Diseases

Alias

Nasopalpebral Lipoma-Coloboma Syndrome

Nasopalpebral Lipoma Coloboma Syndrome	NPLCS
Palpebral Coloboma-Lipoma Syndrome	Palpebral Coloboma Lipoma Syndrome

Achromatopsia 7

ACHM7

Achromatopsia, Type 7

Temple Syndrome

Uniparental Disomy, Maternal, Chromosome 14	Temple Syndrome Due To Paternal 14q32.2 Microdeletion
Paternal Del(14)(Q32.2)	Temple Syndrome Due To Paternal 14q32.2 Hypomethylation
Temple Syndrome Due To Maternal Uniparental Disomy Of Chromosome 14	Upd(14)Mat

Chromosome 2q37 Deletion Syndrome

Albright Hereditary Osteodystrophy-Like Syndrome	2q37 Microdeletion Syndrome
Brachydactyly-Intellectual Disability Syndrome	Deletion 2q37
2q37 Deletion Syndrome	Brachydactyly-Mental Retardation Syndrome
Bdmr	Albright Hereditary Osteodystrophy Type 3
Del(2)(Q37)	Monosomy 2q37qter
Albright'S Hereditary Osteodystrophy-Like Syndrome	Monosomy 2q37
Chromosome Deletion Syndrome 2q37

Pseudohypoparathyroidism, Type Ib

Pseudohypoparathyroidism Type 1b	PHP1B
Pseudohypoparathyroidism Ib	Pseudohypoparathyroidism Type Ib
Php Ib	Pseudohypoparathyroidism 1b

Silver-Russell Syndrome 1

Silver-Russell Syndrome	Russell-Silver Syndrome
Silver-Russell Dwarfism	Rss
SRS1	Srs
Silver Russell Dwarfism	Russell Silver Syndrome
Silver Russell Syndrome

Transient Neonatal Diabetes Mellitus

Diabetes Mellitus, Transient Neonatal	Tndm
Chromosome 6-Associated Transient Diabetes Mellitus	Dmtn
Diabetes Mellitus, 6q24-Related Transient Neonatal	Tndm1
Neonatal Diabetes Mellitus, Transient	Tndm -[Transient Neonatal Diabetes Mellitus]

Kagami-Ogata Syndrome

Paternal Uniparental Disomy Of Chromosome 14	Uniparental Disomy, Paternal, Chromosome 14
Kos	Mca Due To 14q32.2 Maternally Expressed Gene Defect
Paternal Uniparental Disomy 14	Kagami-Ogata Syndrome Due To Maternal 14q32.2 Microdeletion
Maternal Del(14)(Q32.2)	Maternal Monosomy 14q32.2
Kagami-Ogata Syndrome Due To Maternal 14q32.2 Hypermethylation	Kagami-Ogata Syndrome Due To Paternal Uniparental Disomy Of Chromosome 14
Upd(14)Pat

Beckwith-Wiedemann Syndrome

Wiedemann-Beckwith Syndrome	BWS
Exomphalos-Macroglossia-Gigantism Syndrome	Emg Syndrome
Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation	Emg Abnormality
Wbs	Exomphalos Macroglossia Gigantism Syndrome
Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation	Macroglossia Exomphalos Gigantism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16010	ZDBF2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	ZDBF2	VGNC	VGNC:99423
Bos taurus	ZDBF2	VGNC	VGNC:56156
Mus musculus	ZDBF2	MGD	MGI:1921134
Felis catus	ZDBF2	VGNC	VGNC:107692
Canis familiaris	ZDBF2	VGNC	VGNC:48576
Rattus norvegicus	ZDBF2	RGD	RGD:1560005

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