2. Gene
  3. USP37 - ubiquitin specific peptidase 37 Gene

USP37 - ubiquitin specific peptidase 37 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 57695 | Gene type: protein coding

About USP37

This gene has 11 transcripts (splice variants), 205 orthologues and 71 paralogues. Broad expression in testis (RPKM 8.0), small intestine (RPKM 5.9) and 25 other tissues.

Summary

Enables cysteine-type endopeptidase activity; protein kinase binding activity; and thiol-dependent Deubiquitinase. Involved in G1/S transition of mitotic cell cycle; protein deubiquitination; and regulation of DNA replication. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

USP37 Products(1)

mRNA Protein Name
NM_020935.3 NP_065986.3 ubiquitin carboxyl-terminal hydrolase 37

USP37 Protein Structure

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (341 - 948)

UIM

UIM: Ubiquitin interaction motif (703 - 716)

UIM

UIM: Ubiquitin interaction motif (806 - 822)

UIM

UIM: Ubiquitin interaction motif (828 - 844)

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  • 979 a.a.
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 37

deubiquitinating enzyme 37

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15548 USP37 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus USP37 VGNC VGNC:36726
Macaca mulatta USP37 VGNC VGNC:79220
Rattus norvegicus USP37 RGD RGD:2319715
Mus musculus USP37 MGD MGI:2442483
Canis familiaris USP37 VGNC VGNC:48192
Felis catus USP37 VGNC VGNC:66883
Others USP37 NCBI