2. Gene
  3. RAB40C - RAB40C, member RAS oncogene family Gene

RAB40C - RAB40C, member RAS oncogene family Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as RARL; RASL8C

Gene ID: 57799 | Gene type: protein coding

About RAB40C

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:589,357-629,268 (from NCBI)

This gene has 12 transcripts (splice variants), 241 orthologues and 68 paralogues. Ubiquitous expression in skin (RPKM 11.6), brain (RPKM 8.2) and 25 other tissues.

Summary

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in protein localization to plasma membrane. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in endosome; plasma membrane; and synaptic vesicle. [provided by Alliance of Genome Resources, Apr 2022]

RAB40C Products(5)

mRNA Protein Name
NM_001172663.2 NP_001166134.1 ras-related protein Rab-40C isoform a
NM_001172664.2 NP_001166135.1 ras-related protein Rab-40C isoform a
NM_001172665.2 NP_001166136.1 ras-related protein Rab-40C isoform a
NM_001172666.2 NP_001166137.1 ras-related protein Rab-40C isoform b
NM_021168.5 NP_066991.3 ras-related protein Rab-40C isoform a
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
colocalizes with Golgi apparatus IDA
IDA: Inferred from direct assay
34469730 GOA
colocalizes with lipid droplet IDA
IDA: Inferred from direct assay
34469730 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB40C Protein Structure

Ras

Ras: Ras family (16 - 174)

SOCS_box

SOCS_box: SOCS box (189 - 223)

  • 0
  • 100
  • 200
  • 281 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-40C

RAR (RAS like GTPASE) like

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11564 RAB40C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RAB40C VGNC VGNC:33656
Mus musculus RAB40C MGD MGI:2183454
Felis catus RAB40C VGNC VGNC:80678
Rattus norvegicus RAB40C RGD RGD:727914
Macaca mulatta RAB40C VGNC VGNC:99580