2. Gene
  3. RGS16 - regulator of G protein signaling 16 Gene

RGS16 - regulator of G protein signaling 16 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RGS-R; A28-RGS14; A28-RGS14P

Gene ID: 6004 | Gene type: protein coding

About RGS16

Cytogenetic location: 1q25.3 Genomic coordinates (GRCh38): 1:182,598,623-182,604,389 (from NCBI)

This gene has 1 transcript (splice variant), 179 orthologues and 23 paralogues. Biased expression in thyroid (RPKM 20.2), lung (RPKM 3.6) and 11 other tissues.

Summary

The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]

RGS16 Products(2)

mRNA Protein Name
XM_024448796.1 XP_024304564.1 regulator of G-protein signaling 16 isoform X1
NM_002928.4 NP_002919.3 regulator of G-protein signaling 16

RGS16 Protein Structure

RGS

RGS: Regulator of G protein signaling domain (65 - 179)

  • 0
  • 100
  • 202 a.a.
Protein Preferred Names Protein Names

regulator of G-protein signaling 16

hRGS-r

regulator of G-protein signalling 16

retinal-specific RGS

retinally abundant regulator of G-protein signaling

Related Diseases

Diseases Alias
Retinitis Pigmentosa 12

RP12

Retinitis Pigmentosa With Or Without Paraarteriolar Preservation Of Retinal Pigment Epithelium

Rp With Or Without Preserved Paraarteriole Retinal Pigment Epithelium

Rp With Or Without Pprpe

Retinitis Pigmentosa-12
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13509 CCG-50014 Inhibitor 99.42% Unkown
HY-U00431 CCG 203769 Inhibitor 99.76% Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RGS16 MGD MGI:108407
Macaca mulatta RGS16 VGNC VGNC:76919
Canis familiaris RGS16 VGNC VGNC:45525
Rattus norvegicus RGS16 RGD RGD:1589741
Felis catus RGS16 VGNC VGNC:107931
Bos taurus RGS16 VGNC VGNC:33915