2. Gene
  3. Gpr52 - G protein-coupled receptor 52 Gene

Gpr52 - G protein-coupled receptor 52 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as EG620246

Gene ID: 620246 | Gene type: protein coding

About Gpr52

Chromosome 1: 160,403,908-160,405,544 reverse strand.GRCm39:CM000994.3

This gene has 1 transcript (splice variant), 88 orthologues, 32 paralogues and is associated with 3 phenotypes. Broad expression in cortex adult (RPKM 1.5), frontal lobe adult (RPKM 1.4) and 15 other tissues.

Summary

Predicted to enable G protein-coupled photoreceptor activity. Acts upstream of or within locomotory behavior. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Orthologous to human GPR52 (G protein-coupled receptor 52). [provided by Alliance of Genome Resources, Apr 2022]

Gpr52 Products(2)

mRNA Protein Name
NM_001368668.1 NP_001355597.1 G-protein coupled receptor 52
NM_001146330.2 NP_001139802.1 G-protein coupled receptor 52
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
24587241 MGI
involved in locomotory behavior IMP
IMP: Inferred from mutant phenotype
28583861 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Gpr52 Protein Structure

7tm_classA_rhodopsin-like

7tm_classA_rhodopsin-like: cd00637 (42 - 320)

7tm_classA_rhodopsin-like

7tm_classA_rhodopsin-like: cd00637 (42 - 67)

7tm_classA_rhodopsin-like

7tm_classA_rhodopsin-like: cd00637 (75 - 101)

7tm_classA_rhodopsin-like

7tm_classA_rhodopsin-like: cd00637 (113 - 143)

7tm_classA_rhodopsin-like

7tm_classA_rhodopsin-like: cd00637 (156 - 175)

7tm_classA_rhodopsin-like

7tm_classA_rhodopsin-like: cd00637 (199 - 224)

7tm_classA_rhodopsin-like

7tm_classA_rhodopsin-like: cd00637 (257 - 287)

7tm_classA_rhodopsin-like

7tm_classA_rhodopsin-like: cd00637 (295 - 320)

  • 0
  • 100
  • 200
  • 300
  • 361 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 52

probable G-protein coupled receptor 52

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101787 TP-024 99.96% Unkown
HY-138639 PW0787 98.79% Unkown
HY-145468 GPR52 antagonist-1 Antagonist 99.80% Unkown
HY-154980 GPR52 receptor modulator 1 Modulator 99.85% Unkown
HY-147395 GPR52 agonist-1 Agonist 99.76% Unkown
HY-163671 PW0729 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr52 NCBI NCBI:9293