2. Gene
  3. LHPP - phospholysine phosphohistidine inorganic pyrophosphate phosphatase Gene

LHPP - phospholysine phosphohistidine inorganic pyrophosphate phosphatase Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HDHD2B

Gene ID: 64077 | Gene type: protein coding

About LHPP

Cytogenetic location: 10q26.13 Genomic coordinates (GRCh38): 10:124,461,823-124,614,141 (from NCBI)

This gene has 9 transcripts (splice variants), 196 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 7.5), kidney (RPKM 4.5) and 25 other tissues.

Summary

Enables inorganic diphosphatase activity and protein homodimerization activity. Involved in phosphate-containing compound metabolic process. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

LHPP Products(4)

mRNA Protein Name
NM_001167880.2 NP_001161352.1 phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform 2
NM_001318331.2 NP_001305260.1 phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform 3
NM_001318332.2 NP_001305261.1 phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform 4
NM_022126.4 NP_071409.3 phospholysine phosphohistidine inorganic pyrophosphate phosphatase isoform 1

LHPP Protein Structure

Hydrolase_6

Hydrolase_6: Haloacid dehalogenase-like hydrolase (14 - 112)

Hydrolase_like

Hydrolase_like: HAD-hyrolase-like (187 - 260)

  • 0
  • 100
  • 200
  • 270 a.a.
Protein Preferred Names Protein Names

phospholysine phosphohistidine inorganic pyrophosphate phosphatase

hLHPP

Recombinant LHPP Proteins

Cat. No. Product Name Accession Purity
HY-P71632 LHPP Protein, Human (His-SUMO) Q9H008-1 (M1-K270) ≥95%

Related Diseases

Diseases Alias
Melancholia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07630 LHPP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris LHPP VGNC VGNC:42661
Mus musculus LHPP MGD MGI:1923679
Macaca mulatta LHPP VGNC VGNC:74164
Rattus norvegicus LHPP RGD RGD:1359187
Bos taurus LHPP VGNC VGNC:30870
Felis catus LHPP VGNC VGNC:63223
Others LHPP NCBI