EPB41L4A - erythrocyte membrane protein band 4.1 like 4A Gene

Homo sapiens

Also known as NBL4; EPB41L4

Gene ID: 64097 | Gene type: protein coding

About EPB41L4A

Cytogenetic location: 5q22.1-q22.2 Genomic coordinates (GRCh38): 5:112,141,829-112,419,935 (from NCBI)

This gene has 10 transcripts (splice variants), 188 orthologues and 10 paralogues. Ubiquitous expression in gall bladder (RPKM 6.8), thyroid (RPKM 6.5) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the band 4.1 protein superfamily. Members of this superfamily are thought to play an important role in regulating interactions between the Cytoskeleton and plasma membrane, and contain an amino terminal conserved domain that binds glycophorin C. This gene product is thought to be involved in the beta-catenin signaling pathway. [provided by RefSeq, Dec 2016]

EPB41L4A Products(3)

mRNA	Protein	Name
NM_001347887.2	NP_001334816.1	band 4.1-like protein 4A isoform 1
NM_001347888.2	NP_001334817.1	band 4.1-like protein 4A isoform 3
NM_022140.5	NP_071423.4	band 4.1-like protein 4A isoform 2

EPB41L4A Protein Structure

FERM_N

FERM_M

FERM_C

0
200
400
600
686 a.a.

Protein Preferred Names

Protein Names

band 4.1-like protein 4A

erythrocyte protein band 4.1-like 4

Related Diseases

Diseases

Alias

Failure Of Tooth Eruption, Primary

Primary Failure Of Tooth Eruption	PFE
Primary Retention Of Teeth	Unerupted Second Primary Molar
Dental Noneruption	Familial Posterior Openbite Malocclusion
Primary Failure Of Tooth Eruption, Nonsyndromic	Posterior Openbite Malocclusion, Familial
Nonsyndromic Primary Failure Of Eruption	Dental Non-Eruption
Non-Syndromic Primary Failure Of Eruption	Tooth Eruption, Failure, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04414	EPB41L4A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	EPB41L4A	RGD	RGD:1306034
Bos taurus	EPB41L4A	VGNC	VGNC:28523
Mus musculus	EPB41L4A	MGD	MGI:103007
Canis familiaris	EPB41L4A	VGNC	VGNC:40396
Felis catus	EPB41L4A	VGNC	VGNC:61895
Macaca mulatta	EPB41L4A	VGNC	VGNC:72039

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