RAB17 - RAB17, member RAS oncogene family Gene

Homo sapiens

Gene ID: 64284 | Gene type: protein coding

About RAB17

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:237,574,326-237,590,734 (from NCBI)

This gene has 11 transcripts (splice variants), 147 orthologues and 68 paralogues. Biased expression in duodenum (RPKM 20.0), small intestine (RPKM 19.8) and 12 other tissues.

Summary

The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).[supplied by OMIM, Oct 2009]

RAB17 Products(1)

mRNA	Protein	Name
NM_022449.4	NP_071894.1	ras-related protein Rab-17

RAB17 Protein Structure

Ras

0
100
200
212 a.a.

Protein Preferred Names

Protein Names

ras-related protein Rab-17

Related Diseases

Diseases

Alias

Carpenter Syndrome 1

Carpenter Syndrome	Acrocephalopolysyndactyly Type Ii
Acps Ii	CRPT1
Acrocephalopolysyndactyly Type 2	Acrocephalosyndactyly, Type Ii
Acrocephalopolysyndactyly 2	Acps2
Acps 2	Type Ii Acrocephalosyndactyly
Carpenter Syndrome, Type 1	Apert-Crouzon Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11525	RAB17 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	RAB17	VGNC	VGNC:81520
Mus musculus	RAB17	MGD	MGI:104640
Rattus norvegicus	RAB17	RGD	RGD:1562478
Felis catus	RAB17	VGNC	VGNC:80333
Bos taurus	RAB17	VGNC	VGNC:59174
Canis familiaris	RAB17	VGNC	VGNC:45256

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