2. Gene
  3. WIPF3 - WAS/WASL interacting protein family member 3 Gene

WIPF3 - WAS/WASL interacting protein family member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as CR16

Gene ID: 644150 | Gene type: protein coding

About WIPF3

Cytogenetic location: 7p14.3 Genomic coordinates (GRCh38): 7:29,806,508-29,917,061 (from NCBI)

This gene has 2 transcripts (splice variants), 186 orthologues and 2 paralogues. Biased expression in ovary (RPKM 20.0), testis (RPKM 14.2) and 10 other tissues.

Summary

Predicted to enable SH3 domain binding activity and actin binding activity. Predicted to be involved in actin filament-based movement. Predicted to be located in cytosol. Predicted to be active in actin filament. [provided by Alliance of Genome Resources, Apr 2022]

WIPF3 Products(2)

mRNA Protein Name
NM_001080529.3 NP_001073998.2 WAS/WASL-interacting protein family member 3 isoform 1
NM_001391973.1 NP_001378902.1 WAS/WASL-interacting protein family member 3 isoform 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23414517 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WIPF3 Protein Structure

WH2

WH2: WH2 motif (43 - 69)

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  • 483 a.a.
Protein Preferred Names Protein Names

WAS/WASL-interacting protein family member 3

corticosteroids and regional expression protein 16 homolog

WIPF3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
WIPF3 A6NGB9 WASL Homo sapiens O00401
Y2H Fragment Pooling
23414517
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15818 WIPF3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta WIPF3 VGNC VGNC:108453
Bos taurus WIPF3 VGNC VGNC:36941
Felis catus WIPF3 VGNC VGNC:102730
Canis familiaris WIPF3 VGNC VGNC:54799
Mus musculus WIPF3 MGD MGI:3044681
Rattus norvegicus WIPF3 RGD RGD:708559