LINGO3 - leucine rich repeat and Ig domain containing 3 Gene

Homo sapiens

Also known as LERN2; LRRN6B

Gene ID: 645191 | Gene type: protein coding

About LINGO3

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:2,287,164-2,308,154 (from NCBI)

This gene has 2 transcripts (splice variants), 373 orthologues and 10 paralogues. Biased expression in spleen (RPKM 1.7), brain (RPKM 0.7) and 7 other tissues.

Summary

Predicted to be integral component of membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

LINGO3 Products(1)

mRNA	Protein	Name
NM_001101391.3	NP_001094861.1	leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 precursor

LINGO3 Protein Structure

LRRNT

LRR_8

I-set

0
100
200
300
400
500
592 a.a.

Protein Preferred Names

Protein Names

leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3

leucine rich repeat neuronal 6B

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 19

RP19	Retinitis Pigmentosa-19
Retinitis Pigmentosa, Type 19

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07682	LINGO3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	LINGO3	RGD	RGD:1592209
Canis familiaris	LINGO3	VGNC	VGNC:42690
Bos taurus	LINGO3	VGNC	VGNC:30901
Mus musculus	LINGO3	MGD	MGI:3609246

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