SETSIP - SET like protein Gene

Homo sapiens

Also known as SETP18

Gene ID: 646817 | Gene type: protein coding

About SETSIP

This gene has 1 transcript (splice variant), 211 orthologues and 18 paralogues.

Summary

Enables chromatin binding activity. Involved in endothelial cell differentiation and positive regulation of transcription by RNA polymerase II. Located in cytoplasm; lipid droplet; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SETSIP Products(1)

mRNA	Protein	Name
NM_001287737.2	NP_001274666.2	protein SETSIP

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables chromatin binding	IDA IDA: Inferred from direct assay	22869753	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in endothelial cell differentiation	IDA IDA: Inferred from direct assay	22869753	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	22869753	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	22869753	GOA
located in nucleus	IDA IDA: Inferred from direct assay	22869753	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

protein SETSIP

SET nuclear oncogene pseudogene

Related Diseases

Diseases

Alias

Intellectual Developmental Disorder, Autosomal Dominant 58

Mental Retardation, Autosomal Dominant 58

MRD58

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12751	SETSIP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SETSIP	MGD	MGI:1860267
Rattus norvegicus	SETSIP	RGD	RGD:1307467

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