2. Gene
  3. STMP1 - short transmembrane mitochondrial protein 1 Gene

STMP1 - short transmembrane mitochondrial protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as Mm47; C7orf73; PL-5283

Gene ID: 647087 | Gene type: protein coding

About STMP1

Cytogenetic location: 7q33 Genomic coordinates (GRCh38): 7:135,662,514-135,676,416 (from NCBI)

This gene has 4 transcripts (splice variants) and 121 orthologues. Ubiquitous expression in thyroid (RPKM 20.9), testis (RPKM 17.4) and 25 other tissues.

Summary

Predicted to be involved in positive regulation of NLRP3 inflammasome complex assembly and positive regulation of interleukin-1 beta production. Predicted to be located in mitochondrial intermembrane space and mitochondrial outer membrane. Predicted to be active in mitochondrial respirasome. [provided by Alliance of Genome Resources, Apr 2022]

STMP1 Products(1)

mRNA Protein Name
NM_001130929.2 NP_001124401.1 short transmembrane mitochondrial protein 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Reference Source
involved in mitochondrial cytochrome c oxidase assembly IMP
IMP: Inferred from mutant phenotype
35450818 GOA
involved in mitochondrial respirasome assembly IMP
IMP: Inferred from mutant phenotype
35450818 GOA
Cellular Component GO Annotation Evidence Reference Source
is active in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
35450818 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STMP1 Protein Structure

DUF4535

DUF4535: Domain of unknown function (DUF4535) (3 - 45)

  • 0
  • 47 a.a.
Protein Preferred Names Protein Names

short transmembrane mitochondrial protein 1

uncharacterized protein C7orf73

STMP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
STMP1 E0CX11 SGTA Homo sapiens O43765
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13947 STMP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus STMP1 VGNC VGNC:53677
Felis catus STMP1 VGNC VGNC:102708
Mus musculus STMP1 MGD MGI:1914955
Rattus norvegicus STMP1 RGD RGD:1591053