JMJD4 - jumonji domain containing 4 Gene

Homo sapiens

Gene ID: 65094 | Gene type: protein coding

About JMJD4

This gene has 5 transcripts (splice variants), 195 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 7.3), adrenal (RPKM 6.8) and 25 other tissues.

Summary

Enables 2-oxoglutarate-dependent dioxygenase activity. Involved in positive regulation of translational termination and protein hydroxylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

JMJD4 Products(2)

mRNA	Protein	Name
NM_001161465.2	NP_001154937.2	2-oxoglutarate and iron-dependent oxygenase JMJD4 isoform 2
NM_023007.3	NP_075383.3	2-oxoglutarate and iron-dependent oxygenase JMJD4 isoform 1

JMJD4 Protein Structure

Cupin_8

0
100
200
300
400
463 a.a.

Protein Preferred Names

Protein Names

2-oxoglutarate and iron-dependent oxygenase JMJD4

2-oxoglutarate- and Fe(II)-dependent oxygenase

Related Diseases

Diseases

Alias

Intracranial Chondrosarcoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07038	JMJD4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	JMJD4	VGNC	VGNC:63007
Mus musculus	JMJD4	MGD	MGI:2144404
Rattus norvegicus	JMJD4	RGD	RGD:1307186
Bos taurus	JMJD4	VGNC	VGNC:54440
Canis familiaris	JMJD4	VGNC	VGNC:42188
Macaca mulatta	JMJD4	VGNC	VGNC:106393

Name
Email *

	Sorry, but the email address you supplied was invalid.