SPRR2A - small proline rich protein 2A Gene

Homo sapiens

Gene ID: 6700 | Gene type: protein coding

About SPRR2A

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:153,056,120-153,057,512 (from NCBI)

This gene has 1 transcript (splice variant) and 8 orthologues. Restricted expression toward esophagus (RPKM 1789.3).

Summary

Predicted to be involved in keratinization. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SPRR2A Products(1)

mRNA	Protein	Name
NM_005988.3	NP_005979.1	small proline-rich protein 2A

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables lipid binding	IDA IDA: Inferred from direct assay	34735226	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	18155796	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in antibacterial humoral response	IDA IDA: Inferred from direct assay	34735226	GOA
involved in defense response to Gram-positive bacterium	IDA IDA: Inferred from direct assay	34735226	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	16639001	GOA
is active in extracellular region	IDA IDA: Inferred from direct assay	34735226	GOA
is active in secretory granule	IDA IDA: Inferred from direct assay	34735226	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SPRR2A Protein Structure

SPRR2

0
72 a.a.

Protein Preferred Names

Protein Names

small proline-rich protein 2A

44593

Related Diseases

Diseases

Alias

Anus Benign Neoplasm

Anal Neoplasm	Anal Tumors
Neoplasm Of Anus	Anus Neoplasms

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13715	SPRR2A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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