Rps6ka6 - ribosomal protein S6 kinase polypeptide 6 Gene

Mus musculus

Also known as RSK4; S6K-alpha-6; 2610524K04Rik

Gene ID: 67071 | Gene type: protein coding

About Rps6ka6

Chromosome X: 110,297,889-110,447,656 reverse strand.GRCm39:CM001013.3

This gene has 11 transcripts (splice variants), 207 orthologues, 7 paralogues and is associated with 9 phenotypes. Biased expression in placenta adult (RPKM 15.3), CNS E11.5 (RPKM 4.6) and 7 other tissues.

Summary

Predicted to enable ribosomal protein S6 kinase activity. Involved in negative regulation of ERK1 and ERK2 cascade; negative regulation of embryonic development; and negative regulation of mesoderm development. Predicted to be located in fibrillar center and mitochondrion. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in several structures, including genitourinary system; nervous system; nose; respiratory system; and thymus primordium. Orthologous to human RPS6KA6 (ribosomal protein S6 kinase A6). [provided by Alliance of Genome Resources, Apr 2022]

Rps6ka6 Products(3)

mRNA	Protein	Name
NM_001398774.1	NP_001385703.1	ribosomal protein S6 kinase alpha-6 isoform 2
NM_001374707.3	NP_001361636.2	ribosomal protein S6 kinase alpha-6 isoform 2
NM_025949.3	NP_080225.2	ribosomal protein S6 kinase alpha-6 isoform 1

Rps6ka6 Protein Structure

STKc_RSK_N

STKc_RSK_C

0
200
400
600
800
860 a.a.

Protein Preferred Names

Protein Names

ribosomal protein S6 kinase alpha-6

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12259	RPS6KA6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS12260	Rps6ka6 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS12261	Rps6ka6 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rps6ka6	NCBI	NCBI:27330

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