2. Gene
  3. Rgs8 - regulator of G-protein signaling 8 Gene

Rgs8 - regulator of G-protein signaling 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 6530413N01Rik

Gene ID: 67792 | Gene type: protein coding

About Rgs8

Chromosome 1: 153,528,771-153,576,069 forward strand.GRCm39:CM000994.3

This gene has 10 transcripts (splice variants), 199 orthologues and 23 paralogues. Biased expression in cerebellum adult (RPKM 84.), cortex adult (RPKM 9.6) and 4 other tissues.

Summary

Predicted to enable G-protein alpha-subunit binding activity and GTPase activator activity. Predicted to be involved in G protein-coupled acetylcholine receptor signaling pathway; positive regulation of GTPase activity; and regulation of Dopamine Receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in dendrite; neuronal cell body membrane; and nucleus. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in central nervous system and retina. Orthologous to human RGS8 (regulator of G protein signaling 8). [provided by Alliance of Genome Resources, Apr 2022]

Rgs8 Products(3)

mRNA Protein Name
NM_026380.3 NP_080656.2 regulator of G-protein signaling 8 isoform 1
NM_001347115.1 NP_001334044.1 regulator of G-protein signaling 8 isoform 2
NM_001357525.1 NP_001344454.1 regulator of G-protein signaling 8 isoform 1

Rgs8 Protein Structure

RGS_RGS8

RGS_RGS8: cd08711 (45 - 169)

  • 0
  • 100
  • 180 a.a.
Protein Preferred Names Protein Names

regulator of G-protein signaling 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13509 CCG-50014 Inhibitor 99.42% Unkown
HY-U00431 CCG 203769 Inhibitor 99.76% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rgs8 NCBI NCBI:85397