TCEA3 - transcription elongation factor A3 Gene

Homo sapiens

Also known as TFIIS; TFIIS.H

Gene ID: 6920 | Gene type: protein coding

About TCEA3

Cytogenetic location: 1p36.12 Genomic coordinates (GRCh38): 1:23,380,909-23,424,748 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 221 orthologues and 3 paralogues. Ubiquitous expression in colon (RPKM 19.3), ovary (RPKM 18.5) and 23 other tissues.

Summary

Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated and transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

TCEA3 Products(1)

mRNA	Protein	Name
NM_003196.3	NP_003187.1	transcription elongation factor A protein 3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TCEA3 Protein Structure

Med26

TFIIS_M

TFIIS_C

0
100
200
300
348 a.a.

Protein Preferred Names

Protein Names

transcription elongation factor A protein 3

rhabdomyosarcoma antigen MU-RMS-40.22

Related Diseases

Diseases

Alias

Spastic Paraplegia 24, Autosomal Recessive

SPG24	Spastic Paraplegia 24
Hereditary Spastic Paraplegia 24	Autosomal Recessive Spastic Paraplegia Type 24
Autosomal Recessive Spastic Paraplegia 24

Cockayne Syndrome

Cockayne'S Syndrome	Dwarfism-Retinal Atrophy-Deafness Syndrome
Neill-Dingwall Syndrome	Progeria-Like Syndrome
Progeroid Nanism	Cs

Endocervical Adenocarcinoma

Endocervical Carcinoma

Rhabdomyosarcoma

De Sanctis-Cacchione Syndrome

Xerodermic Idiocy	Xeroderma Pigmentosum With Neurologic Manifestation
DSC	Xerodermic Idiocy Of De Sanctis And Cacchione

Uv-Sensitive Syndrome

Uvss	Uv Sensitive Syndrome
Ultraviolet Sensitive Syndrome

Cockayne Syndrome B

Cockayne Syndrome Type 2	Cockayne Syndrome, Type B
Cockayne Syndrome Type Ii	CSB
Cockayne Syndrome 2	Cockayne Syndrome Type B
Ckn2	Cockayne Syndrome, Type Ii

Xeroderma Pigmentosum, Variant Type

Xeroderma Pigmentosum	XPV
Xeroderma Pigmentosum Variant Type	Xeroderma Pigmentosum With Normal Dna Repair Rates
Photosensitivity With Defective Dna Synthesis	Xp
De Sanctis-Cacchione Syndrome	Desanctis-Cacchione Syndrome
Xeroderma Pigmentosa	Xerodermic Idiocy
Xeroderma Pigmentosum Variant	Xp - [Xeroderma Pigmentosum]
Atrophoderma Pigmentosum

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14293	TCEA3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TCEA3	VGNC	VGNC:78281
Mus musculus	TCEA3	MGD	MGI:1196908
Rattus norvegicus	TCEA3	RGD	RGD:1311369
Canis familiaris	TCEA3	VGNC	VGNC:47184
Bos taurus	TCEA3	VGNC	VGNC:35681
Felis catus	TCEA3	VGNC	VGNC:66016

Name
Email *

	Sorry, but the email address you supplied was invalid.