TLL2 - tolloid like 2 Gene

Homo sapiens

Gene ID: 7093 | Gene type: protein coding

About TLL2

Cytogenetic location: 10q24.1 Genomic coordinates (GRCh38): 10:96,364,608-96,513,926 (from NCBI)

This gene has 3 transcripts (splice variants), 119 orthologues and 35 paralogues. Low expression observed in reference dataset.

Summary

This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin. [provided by RefSeq, Jul 2008]

TLL2 Products(1)

mRNA	Protein	Name
NM_012465.4	NP_036597.1	tolloid-like protein 2 precursor

TLL2 Protein Structure

Astacin

CUB

FXa_inhibition

CUB

EGF_CA

CUB

0
200
400
600
800
1015 a.a.

Protein Preferred Names

Protein Names

tolloid-like protein 2

Related Diseases

Diseases

Alias

Colorado Tick Fever

Mountain Tick Fever	Tick Fever, American Mountain
American Mountain Fever	Colorado Tick Encephalitis
Colorado Tick-Borne Disease	Mountain Fever
American Mountain Tick Fever	Colorado Tick-Borne Fever
Colorado Tick Fever Virus	Non-Exanthematous Tick Fever

Amelogenesis Imperfecta, Hypomaturation Type, Iia2

Amelogenesis Imperfecta Hypomaturation Type 2a2	AI2A2
Amelogenesis Imperfecta, Type Iia2	Amelogenesis Imperfecta Pigmented Hypomaturation Type 2
Amelogenesis Imperfecta, Pigmented Hypomaturation Type, 2	Amelogenesis Imperfecta Hypomaturation Type Iia2
Amelogenesis Imperfecta Type Iia2	Amelogenesis Imperfecta, Hypomaturation Type, 2a2
Amelogenesis Imperfecta 2 Hypocalcification Type

Powassan Encephalitis

Powassan Encephalitis Virus Infection

Anisakiasis

Infection By Anisakis Larva	Anisakis Infection
Pseudoterranova Infection	Anisakiasis Due To Anisakis Simplex
Anisakiasis Due To Pseudoterranova Decipiens	Anisakis Infestation
Infection Due To Anisakis Larvae

Omsk Hemorrhagic Fever

Ohf	Hemorrhagic Fever, Omsk
Ohf - [Omsk Haemorrhagic Fever]	Spring-Fall Haemorrhagic Fever

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14573	TLL2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	TLL2	VGNC	VGNC:56114
Felis catus	TLL2	VGNC	VGNC:66214
Bos taurus	TLL2	VGNC	VGNC:35896
Rattus norvegicus	TLL2	RGD	RGD:1559756
Mus musculus	TLL2	MGD	MGI:1346044
Macaca mulatta	TLL2	VGNC	VGNC:78370

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