Ddit4 - DNA-damage-inducible transcript 4 Gene

Mus musculus

Also known as dig2; REDD1; Rtp801; 5830413E08Rik

Gene ID: 74747 | Gene type: protein coding

About Ddit4

Summary

Enables 14-3-3 protein binding activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Acts upstream of or within several processes, including cellular response to dexamethasone stimulus; negative regulation of TOR signaling; and negative regulation of glycolytic process. Located in mitochondrion. Is expressed in reproductive system and retina nuclear layer. Orthologous to human DDIT4 (DNA damage inducible transcript 4). [provided by Alliance of Genome Resources, Apr 2022]

Ddit4 Products(1)

mRNA	Protein	Name
NM_029083.2	NP_083359.1	DNA damage-inducible transcript 4 protein

Protein Preferred Names

Protein Names

DNA damage-inducible transcript 4 protein

HIF-1 responsive RTP801	HIF-1 responsive protein RTP801
REDD-1	dexamethasone-induced gene 2 protein
protein regulated in development and DNA damage response 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03615	DDIT4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS16246	Ddit4 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS03616	DDIT4L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ddit4	NCBI	NCBI:54541

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