2. Gene
  3. ZNF711 - zinc finger protein 711 Gene

ZNF711 - zinc finger protein 711 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ZNF4; ZNF5; ZNF6; CMPX1; MRX65; MRX97; XLID97; Zfp711; dJ75N13.1

Gene ID: 7552 | Gene type: protein coding

About ZNF711

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:85,243,991-85,273,357 (from NCBI)

This gene has 4 transcripts (splice variants), 218 orthologues, 38 paralogues and is associated with 3 phenotypes. Broad expression in testis (RPKM 23.7), brain (RPKM 10.7) and 16 other tissues.

Summary

This gene encodes a zinc finger protein of unknown function. It bears similarity to a zinc finger protein which acts as a transcriptional activator. This gene lies in a region of the X chromosome which has been associated with cognitive disability. [provided by RefSeq, Jul 2008]

ZNF711 Products(9)

mRNA Protein Name
NM_001330574.2 NP_001317503.1 zinc finger protein 711 isoform 1
NM_001375431.1 NP_001362360.1 zinc finger protein 711 isoform 1
NM_001375432.1 NP_001362361.1 zinc finger protein 711 isoform 1
NM_001375433.1 NP_001362362.1 zinc finger protein 711 isoform 1
NM_001375434.1 NP_001362363.1 zinc finger protein 711 isoform 2
NM_001375435.1 NP_001362364.1 zinc finger protein 711 isoform 2
NM_001375436.1 NP_001362365.1 zinc finger protein 711 isoform 2
NM_001375437.1 NP_001362366.1 zinc finger protein 711 isoform 2
NM_021998.5 NP_068838.3 zinc finger protein 711 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20346720 GOA
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
20346720 GOA
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
20346720 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
31691806 GOA
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
20346720 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF711 Protein Structure

Zfx_Zfy_act

Zfx_Zfy_act: Zfx / Zfy transcription activation region (65 - 368)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (383 - 405)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (414 - 436)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (491 - 516)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (520 - 539)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (562 - 581)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (604 - 629)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (647 - 671)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (691 - 714)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (733 - 756)

  • 0
  • 200
  • 400
  • 600
  • 761 a.a.
Protein Preferred Names Protein Names

zinc finger protein 711

dJ75N13.1 (znf6-like)

Related Diseases

Diseases Alias
Intellectual Developmental Disorder, X-Linked 97

XLID97

Mental Retardation, X-Linked 97

Mrx97

Mrx65

Mrxz

Mental Retardation, X-Linked 65

Mental Retardation, X-Linked, Type 97

Mental Retardation, X-Linked, Znf711-Related
Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability

Non-Specific X-Linked Mental Retardation

X-Linked Non-Specific Intellectual Disability
Non-Syndromic X-Linked Intellectual Disability 97

Mrx65

Mrx97

Mrxz

X-Linked Mental Retardation 65

X-Linked Mental Retardation 97
Partington Syndrome

X-Linked Reticulate Pigmentary Disorder

PRTS

Partington X-Linked Mental Retardation Syndrome

Mrxs1

Mrx36

Intellectual Developmental Disorder, X-Linked, Syndromic 1

Partington Disease

Pdr

Partington-Mulley Syndrome

Russell-Silver Syndrome, X-Linked

Mental Retardation, X-Linked, Syndromic 1

Mental Retardation, X-Linked, With Dystonic Movements, Ataxia, And Seizures

Mental Retardation, X-Linked 36

X-Linked Reticulate Pigmentary Disorder With Systemic Manifestations

X-Linked Russell-Silver Syndrome

Intelectual Disability-Dystonic Movements-Ataxia-Seizures Syndrome

Intellectual Disability, X-Linked, Syndromic 1

Intellectual Disability, X-Linked, With Dystonic Movements, Ataxia, And Seizures

Partington X-Linked Intellectual Disability Syndrome

X-Linked Intellectual Deficit-Dystonia-Dysarthria

X-Linked Mental Retardation With Dystonic Movements, Ataxia, And Seizures

Familial Cutaneous Amyloidosis

X-Linked Cutaneous Amyloidosis

Xlpdr

X-Linked Intellectual Disability-Dystonia-Dysarthria Syndrome

Pigmentary Disorder, Reticulate, With Systemic Manifestations
Syndromic X-Linked Intellectual Disability Siderius Type

Mrxssd

Siderius-Hamel Syndrome

Siderius X-Linked Mental Retardation Syndrome
Familial Behcet-Like Autoinflammatory Syndrome

Autoinflammatory Syndrome, Familial, Behcet-Like

A20 Haploinsufficiency
Corpus Callosum, Agenesis Of, With Abnormal Genitalia

Proud Syndrome

Corpus Callosum Agenesis-Abnormal Genitalia Syndrome

Acc With Abnormal Genitalia

Proud-Levine-Carpenter Syndrome

Microcephaly-Corpus Callosum Agenesis-Abnormal Genitalia Syndrome

Corpus Callosum Agenesis With Abnormal Genitalia

New X-Linked Syndrome With Seizures, Acquired Micrencephaly, And Agenesis Of The Corpus Callosum

Proud Levine Carpenter Syndrome

Acc-Abnormal Genitalia Syndrome

Agenesis Of The Corpus Callosum, With Abnormal Genitalia

ACCAG

Micrencephaly-Corpus Callosum Agenesis-Abnormal Genitalia

Congenital Neurologic Anomalies
Bleeding Disorder, Platelet-Type, 17

Platelet-Type Bleeding Disorder 17

BDPLT17

Thrombasthenia-Thrombocytopenia, Hereditary

Hereditary Thrombasthenia-Thrombocytopenia

Autosomal Dominant Macrothrombocytopenia Gfi1b-Related

Autosomal Dominant Platelet Disorder Gfi1b-Related

Bleeding Disorder, Platelet Type 17
Developmental And Epileptic Encephalopathy 1

Epileptic Encephalopathy, Early Infantile, 1

Infantile Epileptic-Dyskinetic Encephalopathy

DEE1

Eiee1

Issx1

Xmesid

X-Linked Infantile Spasm Syndrome 1

X-Linked Infantile Spasm Syndrome

X-Linked Spasticity-Intellectual Disability-Epilepsy Syndrome

Developmental And Epileptic Encephalopathy, 1

Infantile Epileptic Dyskinetic Encephalopathy

Infantile Spasm Syndrome, X-Linked 1

West Syndrome, X-Linked

Ohtahara Syndrome, X-Linked

Early Infantile Epileptic Encephalopathy 1

Early Infantile Epileptic Encephalopathy-1

Issx

X-Linked Ohtahara Syndrome

X-Linked West Syndrome

Infantile Spasm Syndrome X-Linked 1

Myoclonic Epilepsy X-Linked With Intellectual Disability And Spasticity

Ohtahara Syndrome X-Linked

West Syndrome X-Linked

Encephalopathy, Epileptic, Early Infantile, Type 1
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
Syndromic Intellectual Disability
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16169 ZNF711 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ZNF711 RGD RGD:1562768
Mus musculus ZNF711 MGD MGI:3045342
Bos taurus ZNF711 VGNC VGNC:37337
Canis familiaris ZNF711 VGNC VGNC:48806