CA7 - carbonic anhydrase 7 Gene

Homo sapiens

Also known as CAVII; CA-VII

Gene ID: 766 | Gene type: protein coding

About CA7

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:66,844,414-66,854,147 (from NCBI)

This gene has 3 transcripts (splice variants), 221 orthologues and 14 paralogues. Biased expression in colon (RPKM 16.2), small intestine (RPKM 3.6) and 2 other tissues.

Summary

Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2018]

CA7 Products(3)

mRNA	Protein	Name
NM_001014435.2	NP_001014435.1	carbonic anhydrase 7 isoform 2
NM_001365337.2	NP_001352266.1	carbonic anhydrase 7 isoform 2
NM_005182.3	NP_005173.1	carbonic anhydrase 7 isoform 1

CA7 Protein Structure

Carb_anhydrase

0
100
200
264 a.a.

Protein Preferred Names

Protein Names

carbonic anhydrase 7

carbonate dehydratase VII

Recombinant CA7 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7722	Carbonic Anhydrase 7 Protein, Human (His)	P43166 (M1-A264)	≥95%

Related Diseases

Diseases

Alias

North American Indian Childhood Cirrhosis

NAIC	Hereditary North American Indian Childhood Cirrhosis
Cirrhosis, North American Indian Childhood Type	Cirrhosis, Childhood, North American Indian

Trichosporonosis

Intracranial Hypertension, Idiopathic

Pseudotumor Cerebri	Idiopathic Intracranial Hypertension
Benign Intracranial Hypertension	Iih
Benign Intracran. Hypt.

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01774	CA7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CA7	VGNC	VGNC:26657
Rattus norvegicus	CA7	RGD	RGD:1306842
Macaca mulatta	CA7	VGNC	VGNC:104684
Felis catus	CA7	VGNC	VGNC:60278
Mus musculus	CA7	MGD	MGI:103100
Canis familiaris	CA7	VGNC	VGNC:38615
Others	CA7	NCBI

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