ZNF142 - zinc finger protein 142 Gene

Homo sapiens

Also known as HA4654; pHZ-49; NEDISHM

Gene ID: 7701 | Gene type: protein coding

About ZNF142

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:218,633,329-218,659,623 (from NCBI)

This gene has 6 transcripts (splice variants), 136 orthologues, 36 paralogues and is associated with 2 phenotypes. Ubiquitous expression in brain (RPKM 3.6), testis (RPKM 3.6) and 25 other tissues.

Summary

The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins. It contains 31 C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]

ZNF142 Products(14)

mRNA	Protein	Name
NM_001105537.4	NP_001099007.1	zinc finger protein 142 isoform 1
NM_001366287.2	NP_001353216.1	zinc finger protein 142 isoform 2
NM_001366288.2	NP_001353217.1	zinc finger protein 142 isoform 2
NM_001366289.2	NP_001353218.1	zinc finger protein 142 isoform 2
NM_001366290.3	NP_001353219.1	zinc finger protein 142 isoform 3
NM_001366291.2	NP_001353220.1	zinc finger protein 142 isoform 1
NM_001367339.1	NP_001354268.1	zinc finger protein 142 isoform 4
NM_001367340.1	NP_001354269.1	zinc finger protein 142 isoform 4
NM_001367341.1	NP_001354270.1	zinc finger protein 142 isoform 4
NM_001367342.1	NP_001354271.1	zinc finger protein 142 isoform 4
NM_001379659.1	NP_001366588.1	zinc finger protein 142 isoform 3
NM_001379660.1	NP_001366589.1	zinc finger protein 142 isoform 3
NM_001379661.1	NP_001366590.1	zinc finger protein 142 isoform 3
NM_001379662.1	NP_001366591.1	zinc finger protein 142 isoform 1

ZNF142 Protein Structure

zf-C2H2

zf-C2H2_4

zf-H2C2_2

zf-C2H2

zf-C2H2_4

zf-H2C2_5

zf-C2H2_4

zf-H2C2_5

zf-H2C2_2

zf-C2H2_4

zf-H2C2_5

zf-H2C2_2

zf-C2H2

0
300
600
900
1200
1500
1687 a.a.

Protein Preferred Names

Protein Names

zinc finger protein 142

zinc finger protein 142 (clone pHZ-49)

Related Diseases

Diseases

Alias

Neurodevelopmental Disorder With Impaired Speech And Hyperkinetic Movements

NEDISHM

Pancreatic Squamous Cell Carcinoma

Generalized Epilepsy With Febrile Seizures Plus, Type 7

Febrile Seizures, Familial, 3b	GEFSP7
GEFS+7	Generalized Epilepsy With Febrile Seizures Plus 7
Gefs+, Type 7	Generalised Epilepsy With Febrile Seizures Plus 7
Generalised Epilepsy With Febrile Seizures Plus Type 7	Generalized Epilepsy With Febrile Seizures Plus Type 7
FEB3B	Familial Febrile Convulsions 3
Gefs+ Type 7	Epilepsy, Generalized, With Febrile Seizures Plus, Type 7
Generalized Epilepsy With Febrile Seizures Plus, 7

Dystonia

Dystonic Disease	Dystonic Disorder
Dystonia Disorders	Neuroleptic Dyskinesia

Spastic Paraplegia 48, Autosomal Recessive

SPG48	Hereditary Spastic Paraplegia 48
Autosomal Recessive Spastic Paraplegia Type 48	Autosomal Recessive Spastic Paraplegia 48
Paraplegia, Spastic, Type 48, Autosomal Recessive

Cerebral Creatine Deficiency Syndrome

Deficiency, Cerebral Creatine, Syndrome

Cockayne Syndrome A

Cockayne Syndrome Type 1	Cockayne Syndrome, Type A
Cockayne Syndrome Type I	CSA
Cockayne Syndrome Classic Form	Cockayne Syndrome Classical
Cockayne Syndrome Type A	Ckn1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16102	ZNF142 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ZNF142	RGD	RGD:1309648
Mus musculus	ZNF142	MGD	MGI:1924514
Macaca mulatta	ZNF142	VGNC	VGNC:78844
Canis familiaris	ZNF142	VGNC	VGNC:48660
Bos taurus	ZNF142	VGNC	VGNC:37211

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