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7733

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Natural
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Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155266

    E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-5-C10-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-5-C10-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-5-C10-NH2 hydrochloride
  • HY-N7733

    Calmodulin Inflammation/Immunology
    Fasciculic acid A is a steroid that can be isolated from Hypholoma lateritium. Fasciculic acid B has antiinflammatory and calmodulin antagonistic activity .
    Fasciculic acid A
  • HY-Z7733

    Desmethylcarvedilol; BM-14242

    Calcium Channel Metabolic Disease
    O-Desmethylcarvedilol (Desmethylcarvedilol) is an active metabolite of the non-selective β-adrenergic receptor (β-AR) antagonist Carvedilol (HY-B0006). O-Desmethylcarvedilol inhibits store-overload-induced calcium release in HEK293 cells expressing the ryanodine receptor 2 (RyR2) R4496C (RyR2 R4496C) mutation (IC50 = 7.62 µM). O-Desmethylcarvedilol reduces increases in heart rate and prevents decreases in diastolic blood pressure induced by Isoproterenol (HY-B0468) in conscious rabbits (ED50s = 32 and 5 µg/kg, respectively) .
    O-Desmethylcarvedilol

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