2. Gene
  3. ERI3 - ERI1 exoribonuclease family member 3 Gene

ERI3 - ERI1 exoribonuclease family member 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PINT1; PRNPIP

Gene ID: 79033 | Gene type: protein coding

About ERI3

Cytogenetic location: 1p34.1 Genomic coordinates (GRCh38): 1:44,221,070-44,355,279 (from NCBI)

This gene has 10 transcripts (splice variants), 133 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 26.0), testis (RPKM 24.6) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). [provided by Alliance of Genome Resources, Apr 2022]

ERI3 Products(5)

mRNA Protein Name
NM_001301698.2 NP_001288627.1 ERI1 exoribonuclease 3 isoform 2
NM_001301699.1 NP_001288628.1 ERI1 exoribonuclease 3 isoform 2
NM_001301700.1 NP_001288629.1 ERI1 exoribonuclease 3 isoform 3
NM_001301701.1 NP_001288630.1 ERI1 exoribonuclease 3 isoform 4
NM_024066.3 NP_076971.1 ERI1 exoribonuclease 3 isoform 1

ERI3 Protein Structure

RNase_T

RNase_T: Exonuclease (147 - 319)

  • 0
  • 100
  • 200
  • 300
  • 337 a.a.
Protein Preferred Names Protein Names

ERI1 exoribonuclease 3

enhanced RNAi three prime mRNA exonuclease homolog 3

Related Diseases

Diseases Alias
Kuru

Kuru, Susceptibility To

Kuru Encephalopathy

Kuru Encephalitis

Kuru Disease
Chronic Wasting Disease

Wasting Disease, Chronic
Fatal Familial Insomnia

Insomnia, Fatal Familial

FFI

Familial Fatal Insomnia

Insomnia Familial Fatal

Insomnia Fatal Familial

Insomnia, Fatal, Familial

Ffi - [Fatal Familial Insomnia]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04498 ERI3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ERI3 VGNC VGNC:55169
Rattus norvegicus ERI3 RGD RGD:1595859
Mus musculus ERI3 MGD MGI:2153887
Felis catus ERI3 VGNC VGNC:80199
Macaca mulatta ERI3 VGNC VGNC:72288
Canis familiaris ERI3 VGNC VGNC:54203