2. Gene
  3. Lias - lipoic acid synthetase Gene

Lias - lipoic acid synthetase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as LS; 7a5ex; lip-syn; 2900022L22Rik; 4933425M12Rik

Gene ID: 79464 | Gene type: protein coding

About Lias

Summary

Enables lipoate synthase activity. Acts upstream of or within several processes, including lipoate biosynthetic process; neural tube closure; and response to lipopolysaccharide. Located in mitochondrion. Is expressed in alimentary system; liver; metanephros; salivary gland; and urinary system. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human LIAS (lipoic acid synthetase). [provided by Alliance of Genome Resources, Apr 2022]

Lias Products(2)

mRNA Protein Name
NM_001310612.1 NP_001297541.1 lipoyl synthase, mitochondrial isoform 2
NM_024471.5 NP_077791.1 lipoyl synthase, mitochondrial isoform 1 precursor
Protein Preferred Names Protein Names

lipoyl synthase, mitochondrial

lipoate synthase

lipoic acid synthase

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07639 LIAS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16259 Lias Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lias NCBI NCBI:11019