TUT7 - terminal uridylyl transferase 7 Gene

Homo sapiens

Also known as PAPD6; TENT3B; ZCCHC6

Gene ID: 79670 | Gene type: protein coding

About TUT7

Cytogenetic location: 9q21.33 Genomic coordinates (GRCh38): 9:86,287,733-86,354,410 (from NCBI)

This gene has 7 transcripts (splice variants), 259 orthologues and 4 paralogues. Ubiquitous expression in prostate (RPKM 7.8), skin (RPKM 6.8) and 25 other tissues.

Summary

Enables RNA uridylyltransferase activity and miRNA binding activity. Involved in RNA metabolic process and negative regulation of transposition, RNA-mediated. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TUT7 Products(4)

mRNA	Protein	Name
NM_001185059.2	NP_001171988.1	terminal uridylyltransferase 7 isoform 1
NM_001185074.2	NP_001172003.1	terminal uridylyltransferase 7 isoform 2
NM_001330718.2	NP_001317647.1	terminal uridylyltransferase 7 isoform 3
NM_024617.4	NP_078893.2	terminal uridylyltransferase 7 isoform 1

TUT7 Protein Structure

PAP_assoc

zf-CCHC

PAP_assoc

zf-CCHC

0
300
600
900
1200
1495 a.a.

Protein Preferred Names

Protein Names

terminal uridylyltransferase 7

PAP associated domain containing 6

Related Diseases

Diseases

Alias

Renal Wilms' Tumor

Nonanaplastic Renal Wilm'S Tumor	Nonanaplastic Renal Wilm'S Tumour
Nonanaplastic Renal Wilms Tumor	Renal Wilms' Tumour

Perlman Syndrome

Nephroblastomatosis, Fetal Ascites, Macrosomia And Wilms Tumor	PRLMNS
Renal Hamartomas, Nephroblastomatosis, And Fetal Gigantism	Nephroblastomatosis Fetal Ascites Macrosomia And Wilms Tumor
Nephroblastomatosis, Fetal Ascites, Macrosomia, And Wilms Tumor	Nephroblastomatosis - Fetal Ascites - Macrosomia - Wilms Tumor
Renal Hamartomas, Nephroblastomatosis And Fetal Gigantism	Nephroblastomatosis-Fetal Ascites-Macrosomia-Wilms Tumor Syndrome
Renal Hamartomas Nephroblastomatosis And Fetal Gigantism	Nephroblastoma
Fetal Macrosomia

Spastic Ataxia 4

Treacher Collins Syndrome 1

Treacher Collins Syndrome	Mandibulofacial Dysostosis
Treacher Collins-Franceschetti Syndrome	Tcof
Tcs	Mfd1
Franceschetti-Klein Syndrome	TCS1
Franceschetti Syndrome	Franceschetti-Zwahlen-Klein Syndrome
Zygoauromandibular Dysplasia	Treacher-Collins Syndrome
Mandibulofacial Dysostosis Without Limb Anomalies	Bilateral And Symmetric Oto-Mandibular Dysplasia

Wilms Tumor 1

Nephroblastoma	Wilms Tumor
WT1	Wilms' Tumor
Bilateral Wilms Tumor	Wilms Tumor, Type 1
Wilms Tumor, Somatic	Adult Nephroblastoma
Wt1 Disorder	Renal Embryonic Tumor
Adult Kidney Wilms Tumor	Childhood Kidney Wilms Tumor
Nonanaplastic Kidney Wilms Tumor

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15278	TUT7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TUT7	VGNC	VGNC:66715
Mus musculus	TUT7	MGD	MGI:2387179
Canis familiaris	TUT7	VGNC	VGNC:48571
Rattus norvegicus	TUT7	RGD	RGD:1586015
Macaca mulatta	TUT7	VGNC	VGNC:79545
Bos taurus	TUT7	VGNC	VGNC:37121

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