1. Gene
  2. GAL3ST4 - galactose-3-O-sulfotransferase 4 Gene

GAL3ST4 - galactose-3-O-sulfotransferase 4 Gene

Homo sapiens

Also known as GAL3ST-4

Gene ID: 79690 | Gene type: protein coding

About GAL3ST4

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,159,244-100,168,617 (from NCBI)

This gene has 8 transcripts (splice variants), 202 orthologues and 3 paralogues. Ubiquitous expression in skin (RPKM 11.3), salivary gland (RPKM 5.3) and 21 other tissues.

Summary

This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This Enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates. [provided by RefSeq, Jul 2008]

GAL3ST4 Products(1)

mRNA Protein Name
NM_024637.5 NP_078913.3 galactose-3-O-sulfotransferase 4

GAL3ST4 Protein Structure

Gal-3-0_sulfotr

Gal-3-0_sulfotr: Galactose-3-O-sulfotransferase (18 - 227)

Gal-3-0_sulfotr

Gal-3-0_sulfotr: Galactose-3-O-sulfotransferase (286 - 469)

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  • 486 a.a.
Protein Preferred Names Protein Names

galactose-3-O-sulfotransferase 4

beta-galactose-3-O-sulfotransferase 4

Related Diseases

Diseases Alias
Fanconi Anemia, Complementation Group G

Fanconi Anemia Complementation Group G

FANCG

Scoliosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris GAL3ST4 VGNC VGNC:54026
Mus musculus GAL3ST4 MGD MGI:1916254
Rattus norvegicus GAL3ST4 RGD RGD:1561105
Macaca mulatta GAL3ST4 VGNC VGNC:72770
Felis catus GAL3ST4 VGNC VGNC:62437
Bos taurus GAL3ST4 VGNC VGNC:29216