2. Gene
  3. ISOC2 - isochorismatase domain containing 2 Gene

ISOC2 - isochorismatase domain containing 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 79763 | Gene type: protein coding

About ISOC2

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:55,452,985-55,461,642 (from NCBI)

This gene has 8 transcripts (splice variants), 191 orthologues and 1 paralogue. Ubiquitous expression in kidney (RPKM 36.5), liver (RPKM 23.7) and 25 other tissues.

Summary

Involved in protein destabilization. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ISOC2 Products(3)

mRNA Protein Name
NM_001136201.2 NP_001129673.1 isochorismatase domain-containing protein 2 isoform 1
NM_001136202.2 NP_001129674.1 isochorismatase domain-containing protein 2 isoform 3
NM_024710.3 NP_078986.1 isochorismatase domain-containing protein 2 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17658461 GOA
Biological Process GO Annotation Evidence Reference Source
involved in protein destabilization IMP
IMP: Inferred from mutant phenotype
17658461 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17658461 GOA
located in nucleus IDA
IDA: Inferred from direct assay
17658461 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ISOC2 Protein Structure

Isochorismatase

Isochorismatase: Isochorismatase family (17 - 162)

  • 0
  • 100
  • 205 a.a.
Protein Preferred Names Protein Names

isochorismatase domain-containing protein 2

isochorismatase domain-containing protein 2, mitochondrial

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06938 ISOC2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ISOC2 VGNC VGNC:30302
Rattus norvegicus ISOC2 RGD RGD:1592677
Canis familiaris ISOC2 VGNC VGNC:42113
Felis catus ISOC2 VGNC VGNC:62979