MOB3B - MOB kinase activator 3B Gene

Homo sapiens

Also known as MOB1D; C9orf35; MOBKL2B

Gene ID: 79817 | Gene type: protein coding

About MOB3B

Cytogenetic location: 9p21.2 Genomic coordinates (GRCh38): 9:27,325,209-27,529,814 (from NCBI)

This gene has 2 transcripts (splice variants), 150 orthologues and 6 paralogues. Ubiquitous expression in ovary (RPKM 14.2), duodenum (RPKM 9.8) and 20 other tissues.

Summary

The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008]

MOB3B Products(1)

mRNA	Protein	Name
NM_024761.5	NP_079037.3	MOB kinase activator 3B

MOB3B Protein Structure

Mob1_phocein

0
100
200
216 a.a.

Protein Preferred Names

Protein Names

MOB kinase activator 3B

MOB kinase activator-like 2B

Related Diseases

Diseases

Alias

Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1

FTDALS1	Frontotemporal Dementia And/Or Motor Neuron Disease
Ftdmnd	Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia
Alsftd	Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis
Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis-1	Frontotemporal Dementia With Motor Neuron Disease
Ftdals	Ftd-Als
Ftd-Mnd	Frontotemporal Dementia With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis With Frontotemporal Dementia 1	Amyotrophic Lateral Sclerosis/Frontotemporal Dementia
Dementia, Frontotemporal, And/Or Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia 1
Frontotemporal Lobar Degeneration	Grn-Related Frontotemporal Dementia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08576	MOB3B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MOB3B	VGNC	VGNC:43303
Felis catus	MOB3B	VGNC	VGNC:63547
Mus musculus	MOB3B	MGD	MGI:2664539
Rattus norvegicus	MOB3B	RGD	RGD:1560696
Bos taurus	MOB3B	VGNC	VGNC:31545

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