SYNPO2L - synaptopodin 2 like Gene

Homo sapiens

Gene ID: 79933 | Gene type: protein coding

About SYNPO2L

This gene has 3 transcripts (splice variants), 272 orthologues and 2 paralogues. Restricted expression toward heart (RPKM 82.2).

Summary

Predicted to enable actin binding activity. Predicted to be involved in several processes, including positive regulation of Rho protein signal transduction; positive regulation of stress fiber assembly; and sarcomere organization. Located in cell junction; cytosol; and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

SYNPO2L Products(2)

mRNA	Protein	Name
NM_001114133.3	NP_001107605.1	synaptopodin 2-like protein isoform a
NM_024875.5	NP_079151.2	synaptopodin 2-like protein isoform b

SYNPO2L Protein Structure

PDZ

0
200
400
600
800
977 a.a.

Protein Preferred Names

Protein Names

synaptopodin 2-like protein

Related Diseases

Diseases

Alias

Familial Atrial Fibrillation

Atrial Fibrillation, Familial	Atfb
Atrial Fibrillation Autosomal Dominant	Autosomal Dominant Atrial Fibrillation
Auricular Fibrillation	Atrial Fibrillation
Atrial Fibrillation, Familial, 1

Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy	Primary Dilated Cardiomyopathy
Idiopathic Dilated Cardiomyopathy	Congestive Cardiomyopathy
Idiopathic Dilation Cardiomyopathy	Primary Familial Dilated Cardiomyopathy
Cardiomyopathy, Dilated	DCM
Cardiomyopathy, Familial Dilated	Dilated Cardiomyopathy, Familial
Hypokinetic Dilated Cardiomyopathy, Familial	Familial Idiopathic Cardiomyopathy
Fdc	Cardiomyopathy, Familial Idiopathic
Idiopathic Cardiomegaly	Dilated Congestive Cardiomyopathy
Chronic Dilated Cardiomyopathy	Ccm - [Congestive Cardiomyopathy]
Cocm - [Congestive Cardiomyopathy]	Dcm - [Dilated Cardiomyopathy]
Dilated-Hypokinetic Cardiomyopathy	Congestive Idiopathic Cardiomyopathy
Primary Idiopathic Dilated Cardiomyopathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14099	SYNPO2L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SYNPO2L	VGNC	VGNC:78199
Bos taurus	SYNPO2L	VGNC	VGNC:54495
Rattus norvegicus	SYNPO2L	RGD	RGD:1565434
Canis familiaris	SYNPO2L	VGNC	VGNC:47036
Mus musculus	SYNPO2L	MGD	MGI:1916010
Felis catus	SYNPO2L	VGNC	VGNC:65890

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