2. Gene
  3. FRMD1 - FERM domain containing 1 Gene

FRMD1 - FERM domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as bA164L23.1

Gene ID: 79981 | Gene type: protein coding

About FRMD1

This gene has 11 transcripts (splice variants) and 149 orthologues. Biased expression in colon (RPKM 2.7), kidney (RPKM 2.0) and 7 other tissues.

Summary

Predicted to be involved in positive regulation of hippo signaling. Predicted to be located in Cytoskeleton. Predicted to be active in cytoplasmic side of apical plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

FRMD1 Products(3)

mRNA Protein Name
NM_001122841.3 NP_001116313.1 FERM domain-containing protein 1 isoform 2
NM_001394681.1 NP_001381610.1 FERM domain-containing protein 1 isoform 3
NM_024919.6 NP_079195.3 FERM domain-containing protein 1 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FRMD1 Protein Structure

FERM_N

FERM_N: FERM N-terminal domain (58 - 147)

FERM_M

FERM_M: FERM central domain (153 - 264)

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  • 549 a.a.
Protein Preferred Names Protein Names

FERM domain-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05099 FRMD1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus FRMD1 VGNC VGNC:102425
Rattus norvegicus FRMD1 RGD RGD:1588779
Bos taurus FRMD1 VGNC VGNC:56363
Macaca mulatta FRMD1 VGNC VGNC:72757