1. Gene
  2. MYO19 - myosin XIX Gene

MYO19 - myosin XIX Gene

Homo sapiens

Also known as MYOHD1

Gene ID: 80179 | Gene type: protein coding

About MYO19

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:36,495,636-36,544,815 (from NCBI)

This gene has 27 transcripts (splice variants), 1 gene allele, 195 orthologues and 43 paralogues. Ubiquitous expression in skin (RPKM 10.8), esophagus (RPKM 7.0) and 25 other tissues.

Summary

Enables actin binding activity. Involved in regulation of cytokinesis and regulation of mitochondrial fission. Acts upstream of or within mitochondrion migration along actin filament. Located in cytosol and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022]

MYO19 Products(3)

mRNA Protein Name
NM_001033580.3 NP_001028752.1 unconventional myosin-XIX isoform 3
NM_001163735.2 NP_001157207.1 unconventional myosin-XIX isoform 2
NM_025109.6 NP_079385.2 unconventional myosin-XIX isoform 1

MYO19 Protein Structure

Myosin_head

Myosin_head: Myosin head (motor domain) (38 - 674)

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  • 970 a.a.
Protein Preferred Names Protein Names

unconventional myosin-XIX

myosin head domain containing 1

Related Diseases

Diseases Alias
Glycosylphosphatidylinositol Biosynthesis Defect 11

GPIBD11

Hyperphosphatasia With Mental Retardation Syndrome 5

Hpmrs5

Hyperphosphatasia With Mental Retardation Syndrome, Type 5

Cleft Palate, Isolated

Cleft Palate

Isolated Cleft Palate

CPI

Cp

Palatoschisis

Cleft Palate Isolated

Uranostaphyloschisis

Congenital Fissure Of Palate

Cleft Of Secondary Palate

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MYO19 RGD RGD:1559961
Macaca mulatta MYO19 VGNC VGNC:75026
Mus musculus MYO19 MGD MGI:1913446
Canis familiaris MYO19 VGNC VGNC:43559
Felis catus MYO19 VGNC VGNC:63686
Bos taurus MYO19 VGNC VGNC:31815