WDCP - WD repeat and coiled coil containing Gene

Homo sapiens

Also known as MMAP; PP384; C2orf44

Gene ID: 80304 | Gene type: protein coding

About WDCP

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:24,029,347-24,047,391 (from NCBI)

This gene has 3 transcripts (splice variants), 204 orthologues and is associated with 52 phenotypes. Ubiquitous expression in testis (RPKM 3.8), lymph node (RPKM 3.7) and 25 other tissues.

Summary

Enables kinase binding activity. Involved in protein complex oligomerization. [provided by Alliance of Genome Resources, Apr 2022]

WDCP Products(2)

mRNA	Protein	Name
NM_001142319.2	NP_001135791.1	WD repeat and coiled-coil-containing protein isoform 2
NM_025203.3	NP_079479.1	WD repeat and coiled-coil-containing protein isoform 1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables kinase binding	IPI IPI: Inferred from physical interaction	25469238	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32814053	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in protein complex oligomerization	IDA IDA: Inferred from direct assay	25469238	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WDCP Protein Structure

WDCP

0
200
400
600
721 a.a.

Protein Preferred Names

Protein Names

WD repeat and coiled-coil-containing protein

WD repeat and coiled-coil-containing protein C2orf44

Related Diseases

Diseases

Alias

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15753	WDCP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	WDCP	RGD	RGD:1563701
Mus musculus	WDCP	MGD	MGI:3040699
Bos taurus	WDCP	VGNC	VGNC:36875
Canis familiaris	WDCP	VGNC	VGNC:48344
Felis catus	WDCP	VGNC	VGNC:67009
Macaca mulatta	WDCP	VGNC	VGNC:79582

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