2. Gene
  3. TTYH3 - tweety family member 3 Gene

TTYH3 - tweety family member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 80727 | Gene type: protein coding

About TTYH3

Cytogenetic location: 7p22.3 Genomic coordinates (GRCh38): 7:2,631,986-2,664,802 (from NCBI)

This gene has 7 transcripts (splice variants), 268 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 20.5), kidney (RPKM 16.0) and 24 other tissues.

Summary

This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel. [provided by RefSeq, Jul 2008]

TTYH3 Products(1)

mRNA Protein Name
NM_025250.3 NP_079526.1 protein tweety homolog 3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
NOT enables chloride channel activity IDA
IDA: Inferred from direct assay
34385445 GOA
enables chloride channel activity IMP
IMP: Inferred from mutant phenotype
15010458 GOA
enables intracellularly calcium-gated chloride channel activity IDA
IDA: Inferred from direct assay
16219661 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
18577513 GOA
NOT enables volume-sensitive anion channel activity IDA
IDA: Inferred from direct assay
34385445 GOA
Biological Process GO Annotation Evidence Reference Source
involved in chloride transport IDA
IDA: Inferred from direct assay
16219661 GOA
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
15010458 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TTYH3 Protein Structure

Tweety

Tweety: Tweety (25 - 425)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 523 a.a.
Protein Preferred Names Protein Names

protein tweety homolog 3

hTTY3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15243 TTYH3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TTYH3 VGNC VGNC:79349
Bos taurus TTYH3 VGNC VGNC:36502
Rattus norvegicus TTYH3 RGD RGD:1309549
Mus musculus TTYH3 MGD MGI:1925589
Felis catus TTYH3 VGNC VGNC:66695
Canis familiaris TTYH3 VGNC VGNC:47985