ACSBG2 - acyl-CoA synthetase bubblegum family member 2 Gene

Homo sapiens

Also known as BGR; BRGL; PRTDNY3; PRTD-NY3

Gene ID: 81616 | Gene type: protein coding

About ACSBG2

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:6,135,633-6,193,091 (from NCBI)

This gene has 15 transcripts (splice variants), 263 orthologues and 12 paralogues. Restricted expression toward testis (RPKM 79.4).

Summary

Enables acyl-CoA hydrolase activity and arachidonate-CoA Ligase activity. Acts upstream of or within fatty acid metabolic process. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

ACSBG2 Products(6)

mRNA	Protein	Name
NM_001289177.2	NP_001276106.1	long-chain-fatty-acid--CoA ligase ACSBG2 isoform a
NM_001289178.2	NP_001276107.1	long-chain-fatty-acid--CoA ligase ACSBG2 isoform a
NM_001289179.2	NP_001276108.1	long-chain-fatty-acid--CoA ligase ACSBG2 isoform b
NM_001289180.2	NP_001276109.1	long-chain-fatty-acid--CoA ligase ACSBG2 isoform c
NM_001321384.2	NP_001308313.1	long-chain-fatty-acid--CoA ligase ACSBG2 isoform d
NM_030924.5	NP_112186.3	long-chain-fatty-acid--CoA ligase ACSBG2 isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables arachidonate-CoA ligase activity	IDA IDA: Inferred from direct assay	16762313	GOA
enables fatty acyl-CoA hydrolase activity	IDA IDA: Inferred from direct assay	16762313	GOA
enables long-chain fatty acid-CoA ligase activity	IDA IDA: Inferred from direct assay	16371355	GOA

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within fatty acid metabolic process	IDA IDA: Inferred from direct assay	16371355	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	16371355	GOA
located in mitochondrion	IDA IDA: Inferred from direct assay	16762313	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ACSBG2 Protein Structure

AMP-binding

0
200
400
600
666 a.a.

Protein Preferred Names

Protein Names

long-chain-fatty-acid--CoA ligase ACSBG2

arachidonate--CoA ligase ACSBG2

Related Diseases

Diseases

Alias

Ceroid Lipofuscinosis, Neuronal, 1

Neuronal Ceroid Lipofuscinosis 1	CLN1
Infantile Neuronal Ceroid Lipofuscinosis	Cln1 Disease
Santavuori-Haltia Disease	Ceroid Lipofuscinosis, Neuronal, 1, Variable Age At Onset
Neuronal Ceroid Lipofuscinosis 1 Variable Age Of Onset	Ceroid Lipofuscinosis Neuronal 1
Cln1 Variable Age At Onset	Infantile Batten Disease
Neuronal Ceroid Lipofuscinosis, Infantile	Hagberg-Santavuori Disease
Incl	Juvenile Neuronal Ceroid Lipofuscinosis With Granular Osmiophilic Deposits
Neuronal Ceroid Lipofuscinosis With Variable Age At Onset	Santavuori Disease
Lipofuscinosis, Ceroid, Neuronal, Type 1	Ceroid Lipofuscinosis, Neuronal 1, Infantile

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00197	ACSBG2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ACSBG2	VGNC	VGNC:54569
Mus musculus	ACSBG2	MGD	MGI:3587728
Macaca mulatta	ACSBG2	VGNC	VGNC:69525
Rattus norvegicus	ACSBG2	RGD	RGD:1588580
Bos taurus	ACSBG2	VGNC	VGNC:25561

Name
Email *

	Sorry, but the email address you supplied was invalid.