2. Gene
  3. SLCO5A1 - solute carrier organic anion transporter family member 5A1 Gene

SLCO5A1 - solute carrier organic anion transporter family member 5A1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as OATPJ; OATP-J; OATP5A1; OATPRP4; OATP-RP4; SLC21A15

Gene ID: 81796 | Gene type: protein coding

About SLCO5A1

Cytogenetic location: 8q13.3 Genomic coordinates (GRCh38): 8:69,667,046-69,834,978 (from NCBI)

This gene has 8 transcripts (splice variants), 277 orthologues and 10 paralogues. Ubiquitous expression in small intestine (RPKM 68.6), ovary (RPKM 66.6) and 25 other tissues.

Summary

This gene encodes a 12 transmembrane domain protein that is a member of the solute carrier organic anion transporter superfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

SLCO5A1 Products(3)

mRNA Protein Name
NM_001146008.2 NP_001139480.1 solute carrier organic anion transporter family member 5A1 isoform 2
NM_001146009.1 NP_001139481.1 solute carrier organic anion transporter family member 5A1 isoform 3
NM_030958.3 NP_112220.2 solute carrier organic anion transporter family member 5A1 isoform 1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
21278488 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLCO5A1 Protein Structure

OATP

OATP: Organic Anion Transporter Polypeptide (OATP) family (128 - 735)

Kazal_2

Kazal_2: Kazal-type serine protease inhibitor domain (561 - 603)

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  • 848 a.a.
Protein Preferred Names Protein Names

solute carrier organic anion transporter family member 5A1

organic anion transporter polypeptide-related protein 4

SLCO5A1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82246 SLCO5A1 Antibody (YA1991) WB, IHC-P Human, Mouse

Related Diseases

Diseases Alias
Mesomelia-Synostoses Syndrome

Mesomelic Dysplasia With Acral Synostoses, Verloes-David-Pfeiffer Type

Verloes-David Syndrome

Chromosome 8q13 Deletion Syndrome

Mesomelic Dysplasia, Syndromic

Dominant Mesomelic Shortness Of Stature With Acral Synostoses, Umbilical Anomalies, And Soft Palate Agenesis

Mesomelia Synostoses

8q13 Microdeletion Syndrome

Del(8)Q(13)

Mesomelia-Synostoses Syndrome, Verloes-David-Pfeiffer Type

Monosomy 8q13
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13360 SLCO5A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SLCO5A1 MGD MGI:2443431
Felis catus SLCO5A1 VGNC VGNC:65449
Macaca mulatta SLCO5A1 VGNC VGNC:77736
Bos taurus SLCO5A1 VGNC VGNC:34956
Rattus norvegicus SLCO5A1 RGD RGD:1307132
Canis familiaris SLCO5A1 VGNC VGNC:46500