2. Gene
  3. RAB34 - RAB34, member RAS oncogene family Gene

RAB34 - RAB34, member RAS oncogene family Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RAH; NARR; RAB39

Gene ID: 83871 | Gene type: protein coding

About RAB34

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:28,714,281-28,718,428 (from NCBI)

This gene has 26 transcripts (splice variants), 191 orthologues and 68 paralogues. Ubiquitous expression in ovary (RPKM 30.9), endometrium (RPKM 28.1) and 23 other tissues.

Summary

This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. An alternatively spliced transcript variant produces the nine-amino acid residue-repeats (NARR) protein, which is a functionally distinct nucleolar protein resulting from a different reading frame. [provided by RefSeq, Dec 2016]

RAB34 Products(9)

mRNA Protein Name
NM_001142624.2 NP_001136096.2 ras-related protein Rab-34 isoform 2
NM_001142625.2 NP_001136097.2 ras-related protein Rab-34 isoform 3
NM_001144942.2 NP_001138414.1 ras-related protein Rab-34 isoform 4
NM_001144943.1 NP_001138415.1 ras-related protein Rab-34 isoform 5
NM_001256276.2 NP_001243205.1 ras-related protein Rab-34 isoform 6
NM_001256277.2 NP_001243206.1 ras-related protein Rab-34 isoform 1
NM_001256278.1 NP_001243207.1 ras-related protein Rab-34 isoform 7
NM_001256281.3 NP_001243210.1 ras-related protein Rab-34 isoform NARR
NM_031934.6 NP_114140.4 ras-related protein Rab-34 isoform 1

RAB34 Protein Structure

Ras

Ras: Ras family (54 - 213)

  • 0
  • 100
  • 200
  • 259 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-34

nine amino-acid residue-repeats

Related Diseases

Diseases Alias
N Syndrome

NSX

Intellectual Disability, Malformations, Chromosome Breakage, And Development Of T-Cell Leukemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11548 RAB34 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RAB34 VGNC VGNC:45277
Rattus norvegicus RAB34 RGD RGD:1305058
Macaca mulatta RAB34 VGNC VGNC:81533
Bos taurus RAB34 VGNC VGNC:106887
Mus musculus RAB34 MGD MGI:104606