PRSS27 - serine protease 27 Gene

Homo sapiens

Also known as MPN; CAPH2

Gene ID: 83886 | Gene type: protein coding

About PRSS27

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,712,422-2,720,224 (from NCBI)

This gene has 5 transcripts (splice variants), 123 orthologues and 14 paralogues. Biased expression in esophagus (RPKM 55.3) and skin (RPKM 0.9).

Summary

This gene is located within a large Protease gene cluster on chromosome 16. It belongs to the group-1 subfamily of serine proteases. The encoded protein is a secreted tryptic serine Protease and is expressed mainly in the pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

PRSS27 Products(2)

mRNA	Protein	Name
NM_001318395.2	NP_001305324.1	serine protease 27 isoform 2
NM_031948.5	NP_114154.1	serine protease 27 isoform 1 precursor

PRSS27 Protein Structure

Trypsin

0
100
200
290 a.a.

Protein Preferred Names

Protein Names

serine protease 27

channel-activating protease 2

Recombinant PRSS27 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77077	Marapsin/Pancreasin Protein, Human (HEK293, His)	Q9BQR3 (A23-K290)	≥95%

Related Diseases

Diseases

Alias

Necrotizing Gastritis

Melnick-Needles Syndrome

MNS	Melnick-Needles Osteodysplasty
Osteodysplasty Of Melnick And Needles	Osteochondrodysplasias

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11252	PRSS27 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	PRSS27	VGNC	VGNC:33417
Rattus norvegicus	PRSS27	RGD	RGD:1303256
Mus musculus	PRSS27	MGD	MGI:2450123
Felis catus	PRSS27	VGNC	VGNC:108374
Others	PRSS27	NCBI

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