FGFBP2 - fibroblast growth factor binding protein 2 Gene

Homo sapiens

Also known as KSP37; HBP17RP

Gene ID: 83888 | Gene type: protein coding

About FGFBP2

Cytogenetic location: 4p15.32 Genomic coordinates (GRCh38): 4:15,960,245-15,963,175 (from NCBI)

This gene has 2 transcripts (splice variants), 152 orthologues and 2 paralogues. Biased expression in bone marrow (RPKM 17.7), spleen (RPKM 6.7) and 7 other tissues.

Summary

This gene encodes a member of the Fibroblast Growth Factor binding protein family. The encoded protein is a serum protein that is selectively secreted by cytotoxic lymphocytes and may be involved in cytotoxic lymphocyte-mediated immunity. An increase in the amount of gene product may be associated with atopic asthma and mild extrinsic asthma.[provided by RefSeq Staff, Oct 2008]

FGFBP2 Products(1)

mRNA	Protein	Name
NM_031950.4	NP_114156.1	fibroblast growth factor-binding protein 2 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FGFBP2 Protein Structure

FGF-BP1

0
100
200
223 a.a.

Protein Preferred Names

Protein Names

fibroblast growth factor-binding protein 2

37 kDa killer-specific secretory protein

Recombinant FGFBP2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77433	FGFBP2 Protein, Human (sf9, His)	Q9BYJ0 (Q20-G223)	≥95%

Related Diseases

Diseases

Alias

Cervical Adenosquamous Carcinoma

Adenosquamous Carcinoma Of Cervix

Adenosquamous Cell Carcinoma Of The Cervix Uteri

Asthma

Chronic Obstructive Asthma	Asthma, Diminished Response To Antileukotriene Treatment In
Bronchial Hyperreactivity	Asthma, Susceptibility To
Asthma, Bronchial	Asthma, Protection Against
Asthma, Nocturnal, Susceptibility To	Nocturnal Asthma
Asthma-Related Traits	Asthma-Related Traits, Susceptibility To
Asthma, Nocturnal	Chronic Obstructive Asthma With Acute Exacerbation
Chronic Obstructive Asthma With Status Asthmaticus	Exercise Induced Asthma
Exercise-Induced Asthma	Bronchial Asthma
Asthma, Exercise-Induced	Idiosyncratic Asthma
Unspecified Asthma With Acute Exacerbation	Asthma, Unspecified, With Stated Status Asthmaticus
Status Asthmaticus Nos	Acute Severe Asthma
Acute Severe Bronchial Asthma	Status Asthma
Status Post Asthmaticus

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04909	FGFBP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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