2. Gene
  3. PSD2 - pleckstrin and Sec7 domain containing 2 Gene

PSD2 - pleckstrin and Sec7 domain containing 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as EFA6C

Gene ID: 84249 | Gene type: protein coding

About PSD2

This gene has 2 transcripts (splice variants), 219 orthologues and 15 paralogues. Biased expression in brain (RPKM 11.2) and testis (RPKM 0.5).

Summary

Predicted to enable guanyl-nucleotide exchange factor activity and phospholipid binding activity. Predicted to be involved in regulation of ARF protein signal transduction and regulation of catalytic activity. Predicted to be located in cleavage furrow and ruffle membrane. Predicted to be active in glutamatergic synapse and postsynapse. [provided by Alliance of Genome Resources, Apr 2022]

PSD2 Products(1)

mRNA Protein Name
NM_032289.4 NP_115665.1 PH and SEC7 domain-containing protein 2

PSD2 Protein Structure

Sec7

Sec7: Sec7 domain (307 - 463)

PH_9

PH_9: Pleckstrin homology domain (514 - 625)

  • 0
  • 200
  • 400
  • 600
  • 771 a.a.
Protein Preferred Names Protein Names

PH and SEC7 domain-containing protein 2

exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 C

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11273 PSD2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris PSD2 VGNC VGNC:45083
Bos taurus PSD2 VGNC VGNC:33432
Mus musculus PSD2 MGD MGI:1921252
Macaca mulatta PSD2 VGNC VGNC:76286
Rattus norvegicus PSD2 RGD RGD:1311075
Felis catus PSD2 VGNC VGNC:102297