1. Gene
  2. ZBED3 - zinc finger BED-type containing 3 Gene

ZBED3 - zinc finger BED-type containing 3 Gene

Homo sapiens
Gene ID: 84327 | Gene type: protein coding

About ZBED3

Cytogenetic location: 5q13.3 Genomic coordinates (GRCh38): 5:77,072,072-77,087,285 (from NCBI)

This gene has 3 transcripts (splice variants) and 51 orthologues. Ubiquitous expression in fat (RPKM 5.0), kidney (RPKM 4.8) and 25 other tissues.

Summary

This gene belongs to a class of genes that arose through hAT DNA transposition and that encode regulatory proteins. This gene is upregulated in lung Cancer tissues, where the encoded protein causes an accumulation of beta-catenin and enhanced lung Cancer cell invasion. In addition, the encoded protein can be secreted and be involved in resistance to Insulin. [provided by RefSeq, Jul 2016]

ZBED3 Products(2)

mRNA Protein Name
NM_001329564.2 NP_001316493.1 zinc finger BED domain-containing protein 3
NM_032367.4 NP_115743.1 zinc finger BED domain-containing protein 3
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in response to glucose IDA
IDA: Inferred from direct assay
24283382 GOA
involved in response to insulin IDA
IDA: Inferred from direct assay
24283382 GOA
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
24283382 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBED3 Protein Structure

zf-BED

zf-BED: BED zinc finger (46 - 98)

  • 0
  • 100
  • 200
  • 234 a.a.
Protein Preferred Names Protein Names

zinc finger BED domain-containing protein 3

2610005H11Rik

Related Diseases

Diseases Alias
Maturity-Onset Diabetes Of The Young

MODY

Maturity Onset Diabetes Mellitus In Young

Mason-Type Diabetes

Mason Type Diabetes

Maturity Onset Diabetes Of The Young

Mody Syndrome

Diabetes Of The Young, Maturity-Onset

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus ZBED3 VGNC VGNC:107034
Rattus norvegicus ZBED3 RGD RGD:1309665
Macaca mulatta ZBED3 VGNC VGNC:79271
Felis catus ZBED3 VGNC VGNC:102365
Mus musculus ZBED3 MGD MGI:1919364