ELOF1 - elongation factor 1 Gene

Homo sapiens

Also known as ELF1

Gene ID: 84337 | Gene type: protein coding

About ELOF1

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:11,553,046-11,559,230 (from NCBI)

This gene has 9 transcripts (splice variants) and 203 orthologues. Broad expression in testis (RPKM 39.1), prostate (RPKM 12.1) and 25 other tissues.

Summary

Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in epigenetic maintenance of chromatin in transcription-competent conformation and transcription elongation from RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2022]

ELOF1 Products(4)

mRNA	Protein	Name
NM_001363673.3	NP_001350602.2	transcription elongation factor 1 homolog
NM_001363674.4	NP_001350603.2	transcription elongation factor 1 homolog
NM_001363675.4	NP_001350604.2	transcription elongation factor 1 homolog
NM_032377.4	NP_115753.1	transcription elongation factor 1 homolog

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16189514	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ELOF1 Protein Structure

Elf1

0
83 a.a.

Protein Preferred Names

Protein Names

transcription elongation factor 1 homolog

ELF1 homolog, elongation factor 1

Related Diseases

Diseases

Alias

Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 2

SEMDJL2	Spondyloepimetaphyseal Dysplasia With Joint Laxity, Leptodactylic Type
Spondyloepimetaphyseal Dysplasia With Multiple Dislocations, Hall Type	Spondyloepimetaphyseal Dysplasia With Joint Laxity Type 2
Spondyloepimetaphyseal Dysplasia With Multiple Dislocations Hall Type	Spondyloepimetaphyseal Dysplasia With Joint Laxity, Hall Type
Semd-Md	Spondyloepimetaphyseal Dysplasia With Joint Laxicity, Hall Type
Spondyloepimetaphyseal Dysplasia With Joint Laxity, 2	Lepto-Semdjl
Spondyloepimetaphyseal Dysplasia With Joint Laxity Hall Type	Spondyloepimetaphyseal Dysplasia With Joint Laxity Leptodactylic Type
Spondyloepimetaphyseal Dysplasia With Multiple Dislocations

Gnathomiasis

Gnathostomiasis	Infectious Disease By Gnathostoma
Gnathostomosis	Wandering Swelling

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04320	ELOF1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ELOF1	MGD	MGI:1913376
Canis familiaris	ELOF1	VGNC	VGNC:40318
Macaca mulatta	ELOF1	VGNC	VGNC:72132
Bos taurus	ELOF1	VGNC	VGNC:28446
Felis catus	ELOF1	VGNC	VGNC:61822
Rattus norvegicus	ELOF1	RGD	RGD:1587399

Name
Email *

	Sorry, but the email address you supplied was invalid.