C15orf48 - chromosome 15 open reading frame 48 Gene

Homo sapiens

Also known as MOCCI; NMES1; FOAP-11; MISTRAV; COXFA4L3; MIR147BHG

Gene ID: 84419 | Gene type: protein coding

About C15orf48

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:45,430,610-45,433,340 (from NCBI)

This gene has 4 transcripts (splice variants), 210 orthologues and 2 paralogues. Biased expression in colon (RPKM 233.7), small intestine (RPKM 89.5) and 9 other tissues.

Summary

This gene was first identified in a study of human esophageal squamous cell carcinoma tissues. Levels of both the message and protein are reduced in carcinoma samples. In adult human tissues, this gene is expressed in the the esophagus, stomach, small intestine, colon and placenta. Alternatively spliced transcript variants that encode the same protein have been identified. [provided by RefSeq, Jun 2012]

C15orf48 Products(2)

mRNA	Protein	Name
NM_032413.4	NP_115789.1	normal mucosa of esophagus-specific gene 1 protein
NM_197955.3	NP_922946.1	normal mucosa of esophagus-specific gene 1 protein

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32814053	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	12209954	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C15orf48 Protein Structure

B12D

0
83 a.a.

Protein Preferred Names

Protein Names

normal mucosa of esophagus-specific gene 1 protein

MIR147B host

Related Diseases

Diseases

Alias

Squamous Cell Carcinoma

Epidermoid Carcinoma	Squamous Cell Cancer
Carcinoma, Squamous Cell	Squamous Cell Skin Cancer
Malignant Squamous Cell Tumor	Squamous Carcinoma
Squamous Cell Epithelioma	Carcinoma Squamous Cell
Neoplasms, Squamous Cell	Squamous Cell Carcinoma - Category
Malignant Squamous Cell Neoplasm	Squamous Cell Carcinoma Of Skin

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01700	C15orf48 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	C15orf48	VGNC	VGNC:59105
Rattus norvegicus	C15orf48	RGD	RGD:1359583
Bos taurus	C15orf48	VGNC	VGNC:52612
Mus musculus	C15orf48	MGD	MGI:3034182
Felis catus	C15orf48	VGNC	VGNC:81016

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