GHDC - GH3 domain containing Gene

Homo sapiens

Also known as LGP1; D11LGP1

Gene ID: 84514 | Gene type: protein coding

About GHDC

Cytogenetic location: 17q21.2 Genomic coordinates (GRCh38): 17:42,189,087-42,194,494 (from NCBI)

This gene has 12 transcripts (splice variants) and 172 orthologues. Ubiquitous expression in kidney (RPKM 16.7), spleen (RPKM 13.2) and 25 other tissues.

Summary

Predicted to enable acid-amino acid Ligase activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

GHDC Products(2)

mRNA	Protein	Name
NM_001142623.2	NP_001136095.1	GH3 domain-containing protein isoform 3 precursor
NM_032484.5	NP_115873.1	GH3 domain-containing protein isoform 1 precursor

GHDC Protein Structure

GH3

0
100
200
300
400
500
530 a.a.

Protein Preferred Names

Protein Names

GH3 domain-containing protein

homolog of mouse LGP1

Related Diseases

Diseases

Alias

Fibrosarcomatous Osteosarcoma

Fibroblastic Osteosarcoma

Fibrosarcomatous Osteogenic Sarcoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05410	GHDC Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	GHDC	VGNC	VGNC:62542
Mus musculus	GHDC	MGD	MGI:1931556
Canis familiaris	GHDC	VGNC	VGNC:41204
Rattus norvegicus	GHDC	RGD	RGD:1308881
Bos taurus	GHDC	VGNC	VGNC:29347
Macaca mulatta	GHDC	VGNC	VGNC:72771

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