IL1F10 - interleukin 1 family member 10 Gene

Homo sapiens

Also known as IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta

Gene ID: 84639 | Gene type: protein coding

About IL1F10

Cytogenetic location: 2q14.1 Genomic coordinates (GRCh38): 2:113,067,970-113,075,843 (from NCBI)

This gene has 3 transcripts (splice variants), 208 orthologues and 7 paralogues. Restricted expression toward skin (RPKM 1.0).

Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

IL1F10 Products(2)

mRNA	Protein	Name
NM_032556.6	NP_115945.4	interleukin-1 family member 10
NM_173161.3	NP_775184.1	interleukin-1 family member 10

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IL1F10 Protein Structure

IL1

0
100
152 a.a.

Protein Preferred Names

Protein Names

interleukin-1 family member 10

FIL1 theta

Recombinant IL1F10 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72570	IL-1F10/IL-38 Protein, Human	AAI03967.1 (M1-W152)	≥95%
HY-P76427	IL-1F10/IL-38 Protein, Human (P.pastoris, His)	Q8WWZ1 (M1-W152)	≥95%
HY-P700129AF	Animal-Free IL-1F10/IL-38 Protein, Human (His)	AAI03967.1 (M1-W152)	≥95%

Related Diseases

Diseases

Alias

Psoriasis 11

PSORS11	Psoriasis Susceptibility 11
Psoriasis	Psoriasis Vulgaris
Psoriasis 11, Susceptibility To	Pv

Impetigo Herpetiformis

Psoriasis 14, Pustular

Generalized Pustular Psoriasis	Gpp
Ditra	Acrodermatitis Continua Of Hallopeau
Palmoplantar Pustulosis	PSORS14
Interleukin 36 Receptor Antagonist Deficiency	Psorp
Pustular Psoriasis 14	Deficiency Of Il-36r Antagonist
Acute Generalised Pustular Psoriasis	Deficiency Of The Interleukin-36 Receptor Antagonist
Generalized Pustular Psoriasis Of Von Zumbusch	Von Zumbusch Psoriasis
Deficiency Of Il-36ra	Psoriasis, Pustular, Generalized
Psoriasis, Pustular, Type 14	Pustulosis Of Palms And Soles
Acute Generalized Pustular Psoriasis	Palmoplantar Pustular Psoriasis
Pustulosis Palmaris Et Plantaris	Ppp - [Palmoplantar Pustulosis]
Pustular Psoriasis Of The Palms And Soles	Pustular Bacterid

Periostitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06719	IL1F10 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	IL1F10	MGD	MGI:2652548
Bos taurus	IL1F10	VGNC	VGNC:52788
Canis familiaris	IL1F10	VGNC	VGNC:49108
Macaca mulatta	IL1F10	VGNC	VGNC:106172
Rattus norvegicus	IL1F10	RGD	RGD:1305635
Others	IL1F10	NCBI

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