KIF2B - kinesin family member 2B Gene

Homo sapiens

Gene ID: 84643 | Gene type: protein coding

About KIF2B

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:53,822,927-53,825,193 (from NCBI)

This gene has 1 transcript (splice variant), 69 orthologues and 41 paralogues.

Summary

Predicted to enable microtubule binding activity and microtubule motor activity. Involved in metaphase plate congression; microtubule depolymerization; and regulation of chromosome segregation. Located in intercellular bridge; mitotic spindle; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

KIF2B Products(1)

mRNA	Protein	Name
NM_032559.5	NP_115948.4	kinesin-like protein KIF2B

KIF2B Protein Structure

Kinesin

0
200
400
600
673 a.a.

Protein Preferred Names

Protein Names

kinesin-like protein KIF2B

kinesin protein

Related Diseases

Diseases

Alias

Charcot-Marie-Tooth Disease

Cmt	Hmsn
Hereditary Motor And Sensory Neuropathy	Pma
Cmt - Charcot-Marie-Tooth Disease	Charcot Marie Tooth Disease
Charcot-Marie-Tooth Hereditary Neuropathy	Charcot-Marie-Tooth Syndrome
Peroneal Muscular Atrophy	Hereditary Motor And Sensory Neuropathies

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07283	KIF2B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	KIF2B	VGNC	VGNC:55618
Macaca mulatta	KIF2B	VGNC	VGNC:73946
Felis catus	KIF2B	VGNC	VGNC:99093
Bos taurus	KIF2B	VGNC	VGNC:30600
Mus musculus	KIF2B	MGD	MGI:1920720
Rattus norvegicus	KIF2B	RGD	RGD:1359248

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